Effects of exercise interventions on executive function in autism spectrum disorder: a three-level meta-analytic review - Report - MDSpire

Impact of Physical Activity Programs on Executive Function in Individuals with Autism Spectrum Disorder: A Comprehensive Three-Tier Meta-Analysis

  • By

  • Jiangdi Su

  • Liang Li

  • Yuchen Wang

  • Tonggang Fan

  • July 20, 2026

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Clinical Report: Impact of Physical Activity Programs on Executive Function in ASD

Overview

This meta-analysis evaluates the effects of exercise interventions on executive function in children and adolescents with autism spectrum disorder (ASD). Results indicate a significant improvement in executive function (g = -0.34, p < 0.0001) based on the analysis of included studies.

Background

Autism spectrum disorder (ASD) is a neurodevelopmental condition that significantly impacts social interaction and communication. Executive function (EF) deficits are core challenges in ASD, affecting daily life and overall development. Exercise interventions have been studied for their potential to enhance EF in this population.

Data Highlights

MeasureEffect Size (g)p-value
Overall EF Improvement-0.34<0.0001
Intervention Duration ≥10 weeksGreatest BenefitsN/A

Key Findings

  • Seventeen studies with 626 participants were included in the analysis.
  • Exercise interventions resulted in a significant improvement in executive function (g = -0.34, p < 0.0001).
  • Low heterogeneity was observed among studies (Q = 50.42, p = 0.268).
  • Only intervention duration significantly moderated the effects, with programs lasting ≥10 weeks showing the largest benefits.
  • Further large-scale studies are needed to clarify dose–response relationships.

Clinical Implications

The findings suggest that exercise interventions may improve executive function in children and adolescents with ASD, particularly with longer intervention durations.

Conclusion

Exercise interventions have been shown to improve executive function in children and adolescents with ASD, particularly when sustained for 10 weeks or more. Further research is necessary to clarify dose–response relationships.

Related Resources & Content

  1. Frontiers in Psychiatry, 2026 -- The impact of physical play-based games on executive functions and social behaviors in children with autism spectrum disorder: a systematic review and meta-analysis
  2. Frontiers in Neurology, 2026 -- The influence of chronic exercise intervention on the executive function of children with neurodevelopmental disorders: a meta-analysis
  3. Frontiers in Psychiatry, 2026 -- Effects of different physical activity modalities on executive function in children with attention deficit hyperactivity disorder: a systematic review and meta-analysis
  4. Frontiers in Psychiatry, 2026 -- Exercise dose architecture as a precision-informed developmental framework in autism spectrum disorder: a narrative review of mechanisms, sex- and development-related heterogeneity, and clinical translation
  5. Physical activity, WHO, 2025 -- Physical activity
  6. Effects of exercise intervention on inhibitory control in children and adolescents with autism spectrum disorders: A systematic review and meta-analysis - PMC
  7. Frontiers, 2025 -- Effects of gymnastics exercises on executive function in children with autism spectrum disorder aged 6 to 9 years: a pilot study of a randomized controlled trial
  8. Physical activity
  9. Effects of exercise intervention on inhibitory control in children and adolescents with autism spectrum disorders: A systematic review and meta-analysis - PMC
  10. Frontiers | Effects of gymnastics exercises on executive function in children with autism spectrum disorder aged 6 to 9 years: a pilot study of a randomized controlled trial

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