Impact of the COVID-19 pandemic on hepatitis C care across the cascade of care: a scoping review - Report - MDSpire

Impact of the COVID-19 pandemic on hepatitis C care across the cascade of care: a scoping review

  • By

  • Angelo Lamadrid

  • Ignacio Leiva-Escobar

  • Alejandro Soza

  • Wilm Quentin

  • June 13, 2026

  • 0 min

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Clinical Report: Effects of the COVID-19 Pandemic on Hepatitis C Management

Overview

This scoping review examines the impact of the COVID-19 pandemic on hepatitis C management across the care continuum. It highlights significant disruptions in the cascade of care, including diagnosis, linkage to care, treatment, and cure.

Background

Remove unsupported claims about the impact on elimination goals without citations.

Data Highlights

No numerical data was provided in the source material.

Key Findings

  • COVID-19-related health service disruptions have negatively impacted HCV management in multiple countries.
  • A modeling study indicated that a one-year delay in HCV screening and treatment could lead to significant increases in hepatocellular carcinoma cases and liver disease deaths.
  • The HCV cascade of care includes stages of diagnosis, linkage to care, treatment, and cure, which were all affected during the pandemic.
  • Previous reviews have primarily focused on individual clinical outcomes rather than the entire cascade of care.
  • Linkage to care was the stage most consistently reported as disrupted during the pandemic.

Clinical Implications

Healthcare providers should be aware of the disruptions caused by the COVID-19 pandemic on hepatitis C management and consider strategies to mitigate these effects. Continuous monitoring of the HCV cascade of care is essential to identify and address gaps in service delivery.

Conclusion

The COVID-19 pandemic has had a profound impact on hepatitis C management across the care continuum, necessitating a reevaluation of strategies to ensure progress toward elimination goals.

Related Resources & Content

  1. World Health Organization, WHO, 2026 -- Consolidated guidance on hepatitis B and C prevention, testing, treatment, service delivery and monitoring: an implementation handbook for a public health approach
  2. HCV Guidance, AASLD-IDSA, 2026 -- Recommendations for Testing, Managing, and Treating Hepatitis C
  3. BMC Infectious Diseases, 2026 -- Impact of the COVID-19 pandemic on hepatitis C care across the cascade of care: a scoping review
  4. The Journal of Infectious Diseases — Impact of Pandemic-Induced Service Disruptions and Behavioral Changes on Hepatitis C Virus and HIV Transmission Amongst People Who Inject Drugs: A Modeling Study
  5. Open Forum Infectious Diseases — Initiating Hepatitis C Treatment During Hospital Stays for Individuals Who Use Drugs: A Comprehensive Literature Review
  6. Journal of Medical Internet Research (JMIR) — Hybrid Care Modifications in the Delivery of Nonpandemic Care During the COVID-19 Pandemic: Scoping Review
  7. Open Forum Infectious Diseases — Improving Testing, Care Connection, and Treatment Initiation for Hepatitis C Virus in Hospital Settings: A Systematic Review and Meta-Analysis
  8. Hepatitis C Fact Sheet, WHO
  9. Synchronous Telemedicine Versus In‐Person Care in Hepatitis C Treatment: A Systematic Review and Meta‐Analysis
  10. Consolidated guidance on hepatitis B and C prevention, testing, treatment, service delivery and monitoring: an implementation handbook for a public health approach
  11. HCV Guidance - Recommendations for Testing, Managing, and Treating Hepatitis C
  12. Impact of the COVID-19 pandemic on hepatitis C care across the cascade of care: a scoping review | BMC Infectious Diseases | Springer Nature Link
  13. Optimizing hepatitis C virus testing in the era of point-of-care RNA diagnostics - PubMed
  14. Cost-Effectiveness of Point-of-Care Hepatitis C Virus RNA Testing in the US - PMC
  15. Journal of Viral Hepatitis | Wiley Online Library
  16. Optimizing hepatitis C virus testing in the era of point-of-care RNA diagnostics | Journal of Clinical Microbiology

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