Clinical Report: Anesthetic Considerations in Breast Cancer with DM

Overview

This case study discusses the perioperative anesthetic management of a 47-year-old woman with anti-TIF1-γ dermatomyositis and breast cancer. The report emphasizes the importance of comprehensive pre-operative assessment and individualized anesthetic strategies.

Background

Dermatomyositis (DM) is a rare autoimmune disease with significant clinical heterogeneity, particularly in its subtypes. The anti-TIF1-γ subtype is notably associated with increased malignancy risk and presents unique anesthetic challenges due to potential multisystem involvement. Understanding these complexities is crucial for optimizing perioperative care in affected patients.

Data Highlights

No numerical data or trial data provided in the article.

Key Findings

• The patient exhibited classic symptoms of TIF1-γ antibody-positive DM, including cutaneous manifestations and dysphagia.
• Comprehensive pre-operative anesthetic assessment was essential due to the patient's multisystem involvement.
• Multidisciplinary consultation was conducted to optimize the patient's condition prior to surgery.
• Post-treatment, the patient's muscle strength improved, allowing for surgical intervention.
• Pre-operative evaluations included pulmonary function tests and echocardiography to assess potential complications.

Clinical Implications

Thorough pre-operative evaluation and individualized anesthetic management are critical for patients with DM undergoing surgery.

Conclusion

This case underscores the importance of tailored anesthetic strategies in managing patients with anti-TIF1-γ dermatomyositis and highlights the need for a multidisciplinary approach in perioperative care.

Related Resources & Content

1. Author(s)/Org, Source, Year -- Title
2. Nature Reviews Rheumatology, 2026 -- Progress made and the road ahead for cancer screening in myositis
3. The Role of Anaesthesia in Tumour Development and Progression
4. the asco post — Techniques for Preventing Taxane-Induced Neuropathy in Breast Cancer
5. The ASCO Post — Techniques for Preventing Taxane-Induced Neuropathy in Breast Cancer
6. Frontiers in Medicine — Editorial: Exploring Cutaneous Drug-Related and Drug-Associated Adverse events: from Clinical Insights to Therapeutic Management
7. The Role of Anaesthesia in Tumour Development and Progression
8. Techniques for Preventing Taxane-Induced Neuropathy in Breast Cancer
9. Progress made and the road ahead for cancer screening in myositis | Nature Reviews Rheumatology
10. Frontiers | Perioperative management of anti–TIF1-γ dermatomyositis in a patient with breast cancer: a case report
11. Toward Individualized Management: A Commentary on Perioperative Systemic Therapy Guidelines in Breast Cancer Surgery and Reconstruction. Comment on Galuia et al. Perioperative Drug Management of Systemic Therapies in Breast Cancer: A Literature Review and Treatment Recommendations. Curr. Oncol. 2025, 32, 154 - PMC