Use of WeChat-based patient-doctor interaction improves patient experience of Helicobacter pylori treatment: a randomized controlled trial - Report - MDSpire

Use of WeChat-based patient-doctor interaction improves patient experience of Helicobacter pylori treatment: a randomized controlled trial

  • By

  • Boshen Lin

  • Wenlin Zhang

  • Jinghui Zhang

  • Minjuan Lin

  • Jing Liu

  • Zhongxue Han

  • Yuming Ding

  • Qingzhou Kong

  • Miao Duan

  • Yueyue Li

  • Xiuli Zuo

  • Yanqing Li

  • May 29, 2026

  • 0 min

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Clinical Report: WeChat-Enabled Patient-Physician Communication Enhances Experience

Overview

The implementation of a WeChat-based patient-doctor interaction system significantly improved patient experience during Helicobacter pylori treatment, with 90.3% of patients in the WPDI group reporting satisfaction compared to 74.9% in the control group. However, treatment outcomes, including eradication rates, were comparable between the two groups, indicating that while communication improved experience, it did not enhance clinical results.

Background

Helicobacter pylori infection is a prevalent global health issue and a known risk factor for gastric cancer. Effective communication between patients and healthcare providers is crucial for improving treatment adherence and overall patient experience. This study explores the impact of a digital communication system on patient outcomes during H. pylori eradication therapy.

Data Highlights

GroupEradication Rate (ITT)Eradication Rate (mITT)Eradication Rate (PP)
WPDI90.4% (198/219)93.4% (198/212)94.2% (194/206)
Control89.5% (196/219)93.3% (196/210)94.6% (192/203)

Key Findings

  • The WPDI group had a satisfaction rate of 90.3% compared to 74.9% in the control group (P < 0.001).
  • Patients in the control group reported higher levels of worry (16.0% vs. 26.1%; P = 0.012) and perturbation (11.7% vs. 22.7%; P = 0.003).
  • Eradication rates were similar between WPDI and control groups across all analysis methods.
  • Compliance and adverse event rates were comparable between both groups, indicating no detriment to treatment safety.
  • This study highlights the importance of patient-doctor communication in enhancing treatment experience.

Clinical Implications

Healthcare providers should consider integrating digital communication tools like WeChat to enhance patient engagement and satisfaction during treatment. While treatment outcomes may not significantly improve, the positive impact on patient experience can lead to better adherence and overall satisfaction, emphasizing the role of effective communication.

Conclusion

The WeChat-based patient-doctor interaction system significantly enhances the patient experience during H. pylori treatment, although it does not significantly improve treatment outcomes. This underscores the importance of effective communication in healthcare.

Related Resources & Content

  1. Frontiers | Use of WeChat-based patient-doctor interaction improves patient experience of Helicobacter pylori treatment: A randomized controlled trial
  2. Official journal of the American College of Gastroenterology | ACG — Treatment of Helicobacter pylori
  3. Infection — Approaches to Treating Helicobacter pylori Infections in European Pediatric Populations: Insights from the EuroPedHp Registry
  4. The ASCO Post — Text Message–Based Prescreening Could Benefit Patients Receiving Immunotherapy
  5. npj Digital Medicine — Tailoring Prostate Cancer Education for Patients Through an EHR-Integrated Large Language Model Agent
  6. The ASCO Post — Lessons of 2 Decades' Experience with CHESS
  7. Text Message–Based Prescreening Could Benefit Patients Receiving Immunotherapy
  8. Tailoring Prostate Cancer Education for Patients Through an EHR-Integrated Large Language Model Agent
  9. Official journal of the American College of Gastroenterology | ACG
  10. Fourteen-day vonoprazan-amoxicillin dual therapy versus 14-day bismuth-based quadruple therapy for Helicobacter pylori treatment: a randomized clinical trial - Jin-Yan Zhang, Jin-Hai Chen, Yu-Lin Huang, Ji Li, Dong Xu, Zhong Xu, Xiao-Yi Lei, 2025
  11. Frontiers | Use of WeChat-based patient-doctor interaction improves patient experience of Helicobacter pylori treatment: A randomized controlled trial

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