Trends and Outcomes of Metabolic Surgery in Adolescents with BMI ≥ 50 vs < 50 kg/m2: A Retrospective Study Using the MBSAQIP Database - Report - MDSpire

Trends and Outcomes of Metabolic Surgery in Adolescents with BMI ≥ 50 vs < 50 kg/m2: A Retrospective Study Using the MBSAQIP Database

  • By

  • Pattharasai Kachornvitaya

  • Mélissa V Wills

  • Juan S Barajas-Gamboa

  • Salvador Navarrete

  • Ricard Corcelles

  • Andrew Strong

  • Suthep Udomsawaengsup

  • Matthew Kroh

  • Jerry Dang

  • Valentin Mocanu

  • July 19, 2025

  • 0 min

Share

Metabolic Surgery Outcomes in Adolescents with Severe Obesity: MBSAQIP Review

Overview

This retrospective study analyzed 30-day postoperative outcomes of metabolic and bariatric surgery (MBS) in adolescents aged 13–18 years with BMI ≥ 50 kg/m2 compared to those with BMI < 50 kg/m2 using the MBSAQIP database from 2020 to 2023. Findings highlight differences in complication rates, operative times, and utilization trends, providing insight into the safety and predictors of serious complications in this high-risk population.

Background

Adolescent obesity, affecting over 20% of US teenagers, is associated with early onset of comorbidities such as type 2 diabetes and hypertension, often persisting into adulthood. Metabolic and bariatric surgery (MBS) is an effective intervention for severe obesity when lifestyle modifications fail, yet its use remains low, especially in adolescents with BMI ≥ 50 kg/m2. This subgroup faces increased perioperative risks and medical complexity, but data on surgical outcomes in this population are limited. The MBSAQIP registry offers a comprehensive dataset to evaluate short-term safety and outcomes of MBS in adolescents stratified by BMI.

Data Highlights

VariableBMI < 50 kg/m2BMI ≥ 50 kg/m2
Age (years)Mean ± SDMean ± SD
Sex (% female)PercentagePercentage
Type 2 Diabetes (%)Lower prevalenceHigher prevalence
Hypertension (%)Lower prevalenceHigher prevalence
Operative Time (minutes)ShorterLonger
Serious Complication Rate (%)LowerHigher
30-day Mortality (%)Very lowVery low

Key Findings

  • Adolescents with BMI ≥ 50 kg/m2 had significantly longer operative times compared to those with BMI < 50 kg/m2.
  • The prevalence of associated medical problems such as type 2 diabetes, hypertension, and obstructive sleep apnea was higher in the BMI ≥ 50 kg/m2 cohort.
  • Serious complications within 30 days post-surgery were more frequent in adolescents with BMI ≥ 50 kg/m2, though overall mortality remained very low.
  • Multivariable analysis identified BMI ≥ 50 kg/m2 as an independent predictor of serious postoperative complications.
  • Despite increased risks, metabolic surgery in adolescents with extreme obesity demonstrated acceptable safety profiles when performed in accredited centers.
  • Utilization of MBS in adolescents remains disproportionately low, especially in those with BMI ≥ 50 kg/m2, despite their high risk for obesity-related morbidity.

Clinical Implications

Clinicians should consider metabolic surgery as a viable and relatively safe option for adolescents with severe obesity, including those with BMI ≥ 50 kg/m2, particularly when non-surgical interventions have failed. Awareness of increased operative times and complication risks in this subgroup can guide perioperative planning and patient counseling. Expanding access to MBS for high-BMI adolescents may reduce long-term obesity-related health burdens.

Conclusion

Metabolic and bariatric surgery in adolescents with BMI ≥ 50 kg/m2 is associated with higher rates of serious complications but remains a safe and effective intervention when performed in specialized centers. These findings support guideline-directed care and may encourage broader utilization of MBS in this vulnerable population.

References

  1. Fryar et al. 2020 -- Prevalence of Obesity Among Adolescents in the United States
  2. Kelly et al. 2013 -- Long-term Health Consequences of Adolescent Obesity
  3. Inge et al. 2016 -- Safety and Efficacy of Bariatric Surgery in Adolescents
  4. Teen-LABS Study Group 2018 -- Outcomes of Bariatric Surgery in Adolescents
  5. ASMBS and AAP Guidelines 2021 -- Metabolic Surgery in Adolescents
  6. MBSAQIP Registry Data 2020-2023 -- Bariatric Surgery Outcomes

Original Source(s)

Related Content