Outcomes and Visual Performance Following the Use of Mini-Monovision Extended Depth of Focus Intraocular Lenses - Report - MDSpire
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Outcomes and Visual Performance Following the Use of Mini-Monovision Extended Depth of Focus Intraocular Lenses

  • By

  • Yubing Huang

  • Min Han

  • Zhuoqing Hu

  • Xinyi Zhang

  • Haokun Qu

  • Zheming Wu

  • Yun Chen

  • Weitao Zheng

  • Lina Wu

  • Ruihong Ju

  • December 25, 2025

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Outcomes and Visual Performance of Mini-Monovision EDOF Intraocular Lenses

Overview

This study compared visual outcomes following bilateral implantation of AcrySof® IQ Vivity® EDOF intraocular lenses using a mini-monovision strategy versus bilateral emmetropia. Results demonstrated that mini-monovision with less than 1.0 D anisometropia improved near vision without compromising distance or intermediate visual acuity and maintained good visual quality.

Background

Myopia prevalence increases with age, leading to greater demand for near-vision correction in elderly patients. Extended depth-of-focus (EDOF) intraocular lenses, such as the AcrySof® IQ Vivity®, extend the range of clear vision but provide suboptimal near vision. Mini-monovision, targeting slight myopia in the non-dominant eye, is used to enhance near vision while preserving distance vision. However, concerns exist regarding potential reductions in contrast sensitivity and stereopsis with monovision strategies.

Data Highlights

ParameterGroup A (Mini-Monovision)Group B (Emmetropia)
Sample Size30 patients31 patients
Near Addition Power (Non-dominant Eye)≥ 0.5 D and < 1.0 DEmmetropia
Follow-up Duration1 month post-op1 month post-op
Visual Acuity AssessmentsUDVA, UIVA, UNVAUDVA, UIVA, UNVA
Visual Quality MeasuresMTF, Strehl RatioMTF, Strehl Ratio

Key Findings

  • Mini-monovision with Vivity IOLs achieved improved uncorrected near visual acuity (UNVA) compared to bilateral emmetropia.
  • Distance (UDVA) and intermediate (UIVA) visual acuities were comparable between mini-monovision and emmetropia groups.
  • Visual quality parameters, including modulation transfer function and Strehl ratio, showed no significant decline with mini-monovision.
  • Anisometropia was maintained below 1.0 diopter to minimize patient discomfort and preserve binocular visual function.
  • No significant intraoperative or postoperative complications were reported in either group.

Clinical Implications

The mini-monovision strategy using AcrySof® IQ Vivity® EDOF IOLs can effectively enhance near vision in cataract patients without compromising distance or intermediate vision or visual quality. Maintaining anisometropia below 1.0 D is critical to avoid adverse effects such as asthenopia or reduced stereopsis. This approach may increase spectacle independence and patient satisfaction postoperatively.

Conclusion

Mini-monovision with EDOF Vivity IOLs offers a balanced solution to improve near vision while preserving overall visual performance and quality. It represents a viable option for patients seeking enhanced spectacle independence after cataract surgery.

Related Resources & Content

  1. Skov AG et al. 2020 -- Surgically induced anisometropia and visual outcomes
  2. Alcon Laboratories -- AcrySof® IQ Vivity® IOL product information
  3. Clinical studies on EDOF IOLs and mini-monovision strategies

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