Comparative analysis of indocyanine green and technetium-99m for sentinel lymph node localization in breast cancer – institutional experience - Report - MDSpire
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Comparative analysis of indocyanine green and technetium-99m for sentinel lymph node localization in breast cancer – institutional experience
Clinical Report: Evaluation of Indocyanine Green versus Technetium-99m for Sentinel Lymph Node Mapping in Breast Cancer
Overview
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Background
Accurate axillary staging is crucial in breast cancer management, with sentinel lymph node biopsy (SLNB) being the standard approach for clinically node-negative patients. Traditional methods using Tc-99m and blue dye, while effective, pose risks related to radiation exposure and logistical challenges. The introduction of ICG fluorescence imaging offers a promising, radiation-free alternative that warrants evaluation.
Data Highlights
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Key Findings
ICG fluorescence achieved a sentinel node detection rate of 90.6%.
Tc-99m had a higher detection rate of 97.1%.
No ICG-related complications or adverse events were reported.
Among patients with positive SLNs, metastatic node detection was 94.1% using ICG.
The study supports the integration of ICG into standard breast cancer surgery protocols.
Clinical Implications
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Conclusion
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