Bladder Contraction Linked to Diffuse Nephrogenic Adenoma: A Case Study
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By
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Ning Xu
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Qi Zhang
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Xiangcheng Qin
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September 9, 2026
Clinical Report: Bladder Contraction Linked to Diffuse Nephrogenic Adenoma
Overview
This case study presents a 52-year-old man with irritative lower urinary tract symptoms linked to diffuse nephrogenic adenoma. Despite initial treatments, the patient's condition progressed, leading to radical cystectomy.
Background
Nephrogenic adenoma is a benign metaplastic lesion predominantly found in adult males, often arising in the bladder. Its association with bladder contracture is rare. Understanding its clinical presentation and management is crucial.
Data Highlights
No numerical data or trial data was provided in the article.
Key Findings
- A 52-year-old male presented with severe irritative urinary symptoms and bladder contracture.
- Cystoscopy revealed numerous papillary tumor-like lesions and bladder-wall thickening.
- Histopathological evaluations confirmed the diagnosis of nephrogenic adenoma.
- Despite empirical antituberculous therapy, symptoms persisted, necessitating surgical intervention.
- Radical cystectomy resulted in significant symptom improvement and enhanced quality of life.
Clinical Implications
This case highlights the recognition of nephrogenic adenoma as a potential cause of bladder contracture.
Conclusion
The case highlights the need for awareness of nephrogenic adenoma in patients with unexplained bladder symptoms.
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Based on findings from:
Bladder contracture associated with diffuse nephrogenic adenoma: a case report
Ning Xu, Qi Zhang, Xiangcheng Qin. Frontiers In Medicine, 2026.
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1936462/full
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