Determinants Affecting Illness Perception in Individuals Diagnosed with Parkinson’s Disease - Report - MDSpire

Determinants Affecting Illness Perception in Individuals Diagnosed with Parkinson’s Disease

  • By

  • Wen Ma

  • Yafeng Cui

  • Yuqing Li

  • Min Zhou

  • Xia Wang

  • Le Xu

  • April 28, 2026

  • 0 min

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Determinants Affecting Illness Perception in Individuals Diagnosed with Parkinson’s Disease

Overview

This study investigates the factors influencing illness perception in patients with Parkinson’s disease, revealing significant negative perceptions particularly related to emotional representation and consequences. Key determinants include gender, marital status, education level, age, disease duration, and H-Y stage.

Background

Parkinson’s disease (PD) is a prevalent neurodegenerative disorder with increasing incidence globally, significantly impacting patients' quality of life and healthcare systems. Understanding illness perception is crucial as it influences patient behavior, treatment adherence, and overall disease management. This study aims to identify the determinants of illness perception to inform targeted interventions.

Data Highlights

VariableMean ScoreStandard Deviation
Emotional Representation21.143.44
Consequence19.453.03

Key Findings

  • Patients with PD exhibit significant negative perceptions regarding their illness.
  • Emotional representation and perceived consequences scored particularly high among participants.
  • Gender, marital status, education level, age, disease duration, and H-Y stage significantly influence illness perception (p < 0.05).
  • Women and individuals with lower education levels are at higher risk for negative illness perceptions.
  • Prolonged disease duration correlates with more negative perceptions of illness.

Clinical Implications

Healthcare professionals should consider the identified determinants of illness perception when developing treatment plans for patients with Parkinson’s disease. Targeted psychological interventions, including enhancing social support and coping skills training, may improve patient outcomes.

Conclusion

The findings highlight the need for tailored interventions to address the negative illness perceptions prevalent among patients with Parkinson’s disease, particularly among vulnerable groups. Understanding these perceptions can enhance patient care and support.

References

  1. Drugs - Real World Outcomes, Springer, 2023 -- Financial Impact of Parkinson’s Disease: A Comprehensive, International Cost-of-Illness Analysis
  2. Brain, Oxford Academic, 2025 -- Impaired reward sensitivity in Parkinson's depression is unresponsive to dopamine treatment
  3. npj Digital Medicine, Nature, 2024 -- Innovative Remote Evaluation of Motor and Cognitive Functions in Parkinson's Disease: Utilizing Large Datasets, Machine Learning, and Telehealth Solutions
  4. Brain, Oxford Academic, 2024 -- Longitudinal Alterations in Cerebral Compensation Influence the Progression of Parkinson's Disease
  5. Overview | Parkinson’s disease in adults | Guidance | NICE, NICE, 2024
  6. Safety and efficacy of continuous subcutaneous foslevodopa-foscarbidopa in patients with advanced Parkinson's disease: a randomised, double-blind, active-controlled, phase 3 trial - PubMed
  7. Overview | Parkinson’s disease in adults | Guidance | NICE
  8. Safety and efficacy of continuous subcutaneous foslevodopa-foscarbidopa in patients with advanced Parkinson's disease: a randomised, double-blind, active-controlled, phase 3 trial - PubMed
  9. TYPE Original Research

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