Association of baseline negative life events and perceived social support with self-stigma in adolescents from Dongying, China - Report - MDSpire

Impact of Initial Negative Life Experiences and Perceived Social Support on Self-Stigma Among Adolescents in Dongying, China

  • By

  • Rongrong Guo

  • Yuqi Yang

  • Yuelin Sun

  • Ruochen Ren

  • Xiaochuan Lu

  • Shengnan Liu

  • Chenxi Liu

  • Xi Wang

  • Xuan Zhao

  • Xiangdong Dong

  • Xiuli Ren

  • Yi Hu

  • Yufang Xing

  • July 17, 2026

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Impact of Initial Negative Life Experiences and Perceived Social Support on Self-Stigma

Overview

This study investigates the gender-specific associations of negative life experiences (NLE) and perceived social support (PSS) with self-stigma among adolescents in Dongying, China. Findings indicate that NLE is significantly associated with higher self-stigma scores in males, while low PSS interacts with self-stigma in females.

Background

Self-stigma is a critical issue among adolescents, leading to various mental health problems. This study addresses a gap in the literature regarding the gender differences in these associations over time.

Data Highlights

MeasureMale (β)Female (β)P-value
Baseline NLE0.0360.019P < 0.001
PSSL and time at Visit3--χ2interaction = 9.05, P = 0.003
PSSM and time at Visit3--χ2interaction = 5.66, P = 0.017
Combined NLE and PSSL0.1990.186P < 0.001

Key Findings

  • Baseline NLE is associated with higher self-stigma scores in males (β = 0.036, P < 0.001).
  • The association of NLE with self-stigma is not significant in females (β = 0.019, P = 0.059).
  • Low PSS and time at Visit3 significantly interact with self-stigma in females (χ2interaction = 9.05, P = 0.003).
  • Moderate PSS and time at Visit3 also interact with self-stigma in females (χ2interaction = 5.66, P = 0.017).
  • Participants experiencing both NLE and low PSS have higher self-stigma scores (β = 0.199 for males; β = 0.186 for females).

Clinical Implications

The findings suggest that interventions aimed at reducing self-stigma should consider gender-specific factors, particularly the role of NLE and PSS. Clinicians should be aware of these dynamics when addressing mental health issues in adolescents.

Conclusion

This study highlights the differential impact of NLE and PSS on self-stigma among adolescents, emphasizing the need for gender-sensitive approaches in mental health interventions.

Related Resources & Content

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  3. Frontiers in Psychiatry, 2026 -- Loneliness, rumination, and adolescent psychological crisis in China: a pilot moderated mediation study
  4. BMC Psychiatry, 2025 -- The effect of bullying victimization trajectory on internet gaming disorder and the mediating role of impaired resilience
  5. WHO, 2024 -- Mental health of adolescents
  6. JAMA Network Open, 2025 -- Interventions to Reduce Mental Health Stigma in Young People: A Systematic Review and Meta-Analysis
  7. Mental health of adolescents
  8. Interventions to Reduce Mental Health Stigma in Young People: A Systematic Review and Meta-Analysis | Psychiatry and Behavioral Health | JAMA Network Open | JAMA Network

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