Case Report: Delirium and complications resulting from the abuse of compound liquorice tablets - Report - MDSpire

Case Report: Delirium and complications resulting from the abuse of compound liquorice tablets

  • By

  • Xiwen Tian

  • Liu Liu

  • Liyao Huang

  • Jubo Yin

  • Yanjuan Zeng

  • Yao Chen

  • Shanghao Yang

  • Xuhui Zhou

  • July 6, 2026

  • 0 min

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Clinical Report: Delirium and Adverse Effects Associated with Misuse of Compound Liquorice Tablets

Overview

This case study highlights a 29-year-old male who developed severe delirium and multiple complications after escalating misuse of compound liquorice tablets.

Background

Compound liquorice tablets, containing opium powder and liquorice, have gained popularity as an easily accessible alternative for cough treatment, particularly during the COVID-19 pandemic. However, the addiction potential and severe adverse effects of this medication are often overlooked in clinical practice.

Data Highlights

No numerical data or trial data was presented in the article.

Key Findings

  • The patient developed delirium characterized by confusion, disorientation, and hallucinations after discontinuing compound liquorice tablets.
  • Withdrawal symptoms included palpitations, hypertension, tremors, and severe hypokalemia.
  • The patient was diagnosed with opioid-induced mental and behavioral disorders according to ICD-10 criteria.
  • Comprehensive management included benzodiazepines, antidepressants, and antipsychotics, leading to resolution of symptoms.
  • This case is the first reported instance of delirium linked to withdrawal from compound liquorice tablets.

Clinical Implications

Healthcare professionals should be aware of the potential for addiction and withdrawal symptoms associated with compound liquorice tablets.

Conclusion

This case report serves as a reminder of the risks associated with compound liquorice tablets.

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  8. The American Psychiatric Association Practice Guideline for the Prevention and Treatment of Delirium - PubMed
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