Clinical Report: A Socioeconomic Analysis of the Worldwide Impact of GERD (1990–2021)

Overview

This report analyzes the global burden of gastroesophageal reflux disease (GERD) from 1990 to 2021, highlighting a significant increase in prevalence and associated disability-adjusted life years (DALYs). The findings underscore the socioeconomic disparities influencing GERD's impact across different regions.

Background

Gastroesophageal reflux disease (GERD) is a major public health issue with a global prevalence ranging from 5% to 25%. It is associated with serious complications that can severely affect patients' quality of life and impose a considerable economic burden on healthcare systems. Understanding the socioeconomic factors influencing GERD is crucial for developing effective prevention and treatment strategies.

Data Highlights

Key Findings

• Global GERD cases increased from 441.57 million in 1990 to 826 million in 2021.
• Women exhibit a slightly higher burden of GERD compared to men.
• Age-standardized prevalence rates are highest in low-middle SDI regions, particularly in Latin America and South Asia.
• Persistent socioeconomic inequalities in GERD burden were noted, with little change in inequality metrics from 1990 to 2021.
• Risk factors such as obesity and sedentary behavior are closely linked to geographic and socioeconomic trends in GERD prevalence.

Clinical Implications

Healthcare professionals should be aware of the rising prevalence of GERD and its socioeconomic determinants. Targeted prevention strategies should be developed, particularly in low-middle SDI regions, to address the growing burden of this disease. Clinicians should also consider the impact of lifestyle factors on GERD management.

Conclusion

The increasing global burden of GERD highlights the need for comprehensive strategies that address both clinical and socioeconomic factors. Continued research and policy development are essential to mitigate the impact of GERD worldwide.

References

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