Efficacy and safety of Tuina therapy for children with combined allergic rhinitis and asthma syndrome in remission: a randomized controlled trial protocol - Report - MDSpire

Efficacy and safety of Tuina therapy for children with combined allergic rhinitis and asthma syndrome in remission: a randomized controlled trial protocol

  • By

  • Xin Yun Chia

  • Junhao Cai

  • Dan Dai

  • Qing Ji

  • Shijian Liu

  • Wenyi Wang

  • Mengran Si

  • Yan Yang

  • Ping Lu

  • Xiaoqiu Wang

  • Sijie Dang

  • Yi Zhong

  • Shuxia Wang

  • Guimao Wang

  • Bin Xiao

  • June 23, 2026

  • 0 min

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Clinical Report: Effectiveness and Safety of Tuina Therapy in Pediatric Patients

Background

Combined allergic rhinitis and asthma syndrome (CARAS) is a significant chronic respiratory condition in children, characterized by the coexistence of allergic rhinitis and asthma. The prevalence of these conditions is high, with allergic rhinitis often preceding asthma development. Current pharmacological treatments have limitations, highlighting the need for safe and effective complementary therapies such as pediatric Tuina.

Data Highlights

ParameterGroupDetails
ParticipantsIntervention92 children aged 6–14 years
Intervention FrequencyTuinaThree times weekly for 4 weeks
Primary OutcomePRQLQ ScoreMeasured for efficacy
Secondary OutcomesC-ACT/ACT ScoreTraditional Chinese Medicine symptom scores
Follow-up DurationAll Groups24 weeks

Key Findings

  • The trial will assess the efficacy of pediatric Tuina in improving CARAS symptoms.
  • Primary outcome measure is the Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ) score.
  • Secondary outcomes include the Childhood Asthma Control Test (C-ACT) and traditional Chinese medicine symptom scores.
  • Safety will be monitored through adverse events during the treatment period.

Clinical Implications

The findings from this trial may provide insights into the role of pediatric Tuina as a complementary therapy for CARAS. If effective, it could offer a non-pharmacological option for managing symptoms in pediatric patients.

Conclusion

This study aims to establish the effectiveness and safety of pediatric Tuina in treating CARAS.

Related Resources & Content

  1. Frontiers in Medicine, 2023 -- Effectiveness and Safety of Tuina Therapy in Pediatric Patients with Remission of Combined Allergic Rhinitis and Asthma Syndrome: A Protocol for a Randomized Controlled Trial
  2. conexiant — Pediatric Allergic Rhinitis: When Meds Fall Short
  3. Frontiers in Neurology — Tuina combined with other therapies for treating insomnia: a systematic review and network meta-analysis
  4. Frontiers in Medicine — Efficacy and safety of MuShengshu in the treatment of mild-to-moderate atopic dermatitis: protocol for a randomized, double-blind, placebo-controlled trial
  5. Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments
  6. SQ House Dust Mite Sublingual Immunotherapy Tablet in Children With Allergic Asthma: A Randomised Phase III Trial
  7. Effectiveness and safety of acupuncture and related therapies for pediatric asthma: a systematic review and meta-analysis - PMC

Original Source(s)

Efficacy and safety of Tuina therapy for children with combined allergic rhinitis and asthma syndrome in remission: a randomized controlled trial protocol

  • by Xin Yun Chia, Junhao Cai, Dan Dai, Qing Ji, Shijian Liu, Wenyi Wang, Mengran Si, Yan Yang, Ping Lu, Xiaoqiu Wang, Sijie Dang, Yi Zhong, Shuxia Wang, Guimao Wang, Bin Xiao

  • June 23, 2026

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