Clinical Report: Assessing Bleeding Risk and Outcomes in Left Main PCI
Overview
This study evaluates the prognostic role of the PRECISE-DAPT score in assessing bleeding risk and clinical outcomes in patients undergoing left main percutaneous coronary intervention (PCI). The findings indicate that high bleeding risk, as determined by the PRECISE-DAPT score, significantly impacts patient outcomes post-PCI.
Background
Left main coronary artery disease poses significant treatment challenges due to the risk of adverse cardiovascular events. While coronary artery bypass grafting has traditionally been the standard treatment, advancements in PCI techniques have made it a viable option for selected patients, particularly in Asian populations. Accurate assessment of bleeding risk is crucial in this context, especially given the high prevalence of comorbidities in patients undergoing LM PCI.
Data Highlights
No numerical data available in the provided text.
Key Findings
The PRECISE-DAPT score is a validated tool for estimating bleeding risk in PCI populations.
Patients were stratified into high bleeding risk (HBR) and non-HBR groups based on their PRECISE-DAPT scores.
High bleeding risk significantly correlates with adverse clinical outcomes post-LM PCI.
Demographic and clinical data were collected from a high-volume tertiary medical center in Taiwan.
Ethical approval was obtained, and informed consent was waived due to the retrospective nature of the study.
Clinical Implications
Clinicians should utilize the PRECISE-DAPT score to assess bleeding risk in patients undergoing left main PCI, as it can guide treatment decisions and improve patient outcomes. Awareness of the implications of high bleeding risk is essential for optimizing dual antiplatelet therapy strategies.
Conclusion
The study underscores the importance of the PRECISE-DAPT score in predicting bleeding risk and its impact on clinical outcomes in left main PCI patients. Further research may enhance understanding of risk stratification in this population.
Related Resources & Content
High bleeding risk and outcomes in left main percutaneous coronary intervention: prognostic value of the PRECISE-DAPT score, BMC Cardiovascular Disorders, 2026 -- https://link.springer.com/article/10.1186/s12872-026-05651-w
Preoperative Dual Antiplatelet Therapy with Aspirin and Ticagrelor in Acute Coronary Syndrome Patients Undergoing Emergency Aortocoronary Bypass Surgery, Clinical Research in Cardiology, 2025 -- https://link.springer.com/article/10.1007/s00392-025-02629-0
Physiological Patterns of Coronary Artery Disease Identified Through Angiography: Effects on Post-Stenting Physiology and Long-Term Clinical Outcomes, Clinical Research in Cardiology, 2024 -- https://link.springer.com/article/10.1007/s00392-024-02500-8
Elevated Plasma Chemokine Levels Correlate with Increased Bleeding Risk in Chronic Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention, Clinical Research in Cardiology, 2025 -- https://link.springer.com/article/10.1007/s00392-025-02675-8
2025 Guideline for Acute Coronary Syndromes - Professional Heart Daily | American Heart Association -- https://professional.heart.org/en/science-news/2025-guideline-for-the-management-of-patients-with-acute-coronary-syndromes/top-things-to-know
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