Clinical Report: Patient KAP Regarding Osteosarcopenia in CKD
Overview
This cross-sectional study of 585 chronic kidney disease (CKD) patients revealed suboptimal knowledge (31.65%), moderate attitudes (68.66%), and moderate practices (55.78%) toward osteosarcopenia. Key demographic and psychosocial factors influenced knowledge scores, which in turn positively impacted attitudes and practices.
Background
Chronic kidney disease (CKD) is a global health crisis characterized by progressive renal dysfunction and systemic complications, notably musculoskeletal disorders such as osteosarcopenia—a syndrome combining sarcopenia and osteoporosis. Osteosarcopenia in CKD patients increases fracture risk and physical decline, necessitating early recognition and integrated management strategies. Patient self-management, supported by adequate knowledge and positive attitudes, is essential for effective prevention and treatment. However, patients' knowledge, attitudes, and practices (KAP) regarding osteosarcopenia remain poorly understood, limiting targeted educational interventions.
Data Highlights
Measure
Mean Score
Maximum Score
Percentage (%)
Knowledge
6.33 ± 5.48
20
31.65
Attitude
34.33 ± 5.98
50
68.66
Practice
27.89 ± 9.82
50
55.78
Key Findings
The mean knowledge score was low at 31.65%, indicating poor patient awareness of osteosarcopenia.
Attitude and practice scores were moderate, at 68.66% and 55.78% respectively, showing some positive disposition and behaviors.
Being single, requiring assistance with daily activities, and bedridden status were associated with lower knowledge scores.
Higher social support and environmental factor scores and greater confidence in preventing osteosarcopenia were independently associated with better knowledge.
Path analysis demonstrated that knowledge positively influenced attitudes (β=0.682) and practices (β=0.523), with attitudes also positively affecting practices (β=0.344).
Knowledge indirectly influenced practice through attitude (β=0.235), highlighting the interdependence of these dimensions.
Clinical Implications
These findings emphasize the need for targeted educational interventions to improve CKD patients' knowledge about osteosarcopenia, which may enhance their attitudes and self-management practices. Clinicians should assess patients’ social support and confidence levels to tailor education effectively. Improving patient awareness and engagement could reduce fracture risk and improve quality of life in this vulnerable population.
Conclusion
Patients with CKD demonstrate suboptimal knowledge and moderate attitudes and practices toward osteosarcopenia. Enhancing patient education and support is critical to improving musculoskeletal health outcomes in CKD.
References
Changji Hui Autonomous Prefecture People’s Hospital Study 2025 -- Patient Awareness, Attitudes, and Practices Regarding Osteosarcopenia in Chronic Kidney Disease
