Efficacy and Safety of Vitamin D in the Treatment of Asthma: An Overview of Systematic Reviews and Meta-Analyses - Report - MDSpire

Efficacy and Safety of Vitamin D in the Treatment of Asthma: An Overview of Systematic Reviews and Meta-Analyses

  • By

  • Liu, Yongxiu

  • Lu, Jiaheng

  • Li, Donghao

  • Wang, Zhuang

  • Zhang, Chi

  • Li, Yuguo

  • Liang, Shuang

  • Yang, Haimiao

  • Gao, Lei

  • May 6, 2026

  • 0 min

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Clinical Report: Assessment of Vitamin D Supplementation for Asthma Management

Overview

Revise to include specific studies that highlight the inconsistency in vitamin D's effects on asthma control and lung function.

Background

Asthma is a prevalent chronic condition that significantly affects patients' quality of life and poses a considerable healthcare burden. Vitamin D's role in immune regulation has led to interest in its potential as an adjunct therapy for asthma management. However, the clinical benefits of vitamin D supplementation in asthma treatment are still debated, necessitating a thorough evaluation of existing evidence.

Data Highlights

Replace placeholder with a summary of key findings from the systematic reviews and meta-analyses.

Key Findings

Rephrase findings to ensure they are directly supported by the source material and clearly articulated.

Clinical Implications

Clinicians should consider vitamin D supplementation as a potential adjunctive treatment for asthma, particularly for patients at risk of exacerbations. However, they should remain cautious due to the variability in evidence quality and the lack of consistent improvements in asthma control and lung function.

Conclusion

Vitamin D supplementation may offer some benefits in reducing asthma exacerbations, but its overall effectiveness in improving asthma management is uncertain. Further research is essential to clarify its role and optimize treatment strategies.

Related Resources & Content

  1. Frontiers in Endocrinology, 2026 -- Editorial: Impact of new vitamin D guidelines on pediatric and adult health: insights, evidence, and implications
  2. conexiant, 2025 -- VA DOD Updates Asthma Framework
  3. Clinical Rheumatology, 2017 -- The Role of Vitamin D Deficiency in Autoantibody Formation Among ASIA Patients with Silicone Breast Implants: A Cohort Analysis and Literature Review
  4. Blood Cancer Journal, 2017 -- Validation of a vitamin D replacement strategy in vitamin D-insufficient patients with lymphoma or chronic lymphocytic leukemia
  5. GINA, 2026 -- GINA 2026 Strategy Report
  6. NCBI Bookshelf, 2026 -- Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN)
  7. Frontiers in Medicine, 2026 -- Efficacy and Safety of Vitamin D in the Treatment of Asthma: An Overview of Systematic Reviews and Meta-Analyses
  8. Frontiers in Nutrition, 2026 -- The efficacy of vitamin D supplementation in the management of childhood asthma: a systematic review and meta-analysis
  9. PMC, 2026 -- Vitamin D supplementation decrease asthma exacerbations in children: a systematic review and meta-analysis of randomized controlled trials
  10. JAMA, 2015 -- Effect of Vitamin D3 on Asthma Treatment Failures in Adults With Symptomatic Asthma and Lower Vitamin D Levels: The VIDA Randomized Clinical Trial
  11. GINA 2026 Strategy Report
  12. Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN)
  13. Frontiers | Efficacy and Safety of Vitamin D in the Treatment of Asthma: An Overview of Systematic Reviews and Meta-Analyses
  14. Frontiers | The efficacy of vitamin D supplementation in the management of childhood asthma: a systematic review and meta-analysis
  15. Vitamin D supplementation decrease asthma exacerbations in children: a systematic review and meta-analysis of randomized controlled trials - PMC
  16. Effect of Vitamin D3 on Asthma Treatment Failures in Adults With Symptomatic Asthma and Lower Vitamin D Levels: The VIDA Randomized Clinical Trial | Asthma | JAMA | JAMA Network

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