Clinical Report: Exposure to Nonessential Environmental Elements and Urologic Cancers
Overview
This comprehensive review and meta-analysis evaluate the associations between exposure to nonessential environmental elements and the risk of urologic cancers.
Background
Urologic cancers are prevalent globally, accounting for a significant percentage of new cancer cases and deaths. While genetic factors contribute to these cancers, a substantial portion of risk is attributed to environmental exposures.
Data Highlights
No specific numerical data or trial data provided in the source material.
Key Findings
Urologic cancers include prostate, kidney, and bladder cancers.
Nonessential elements like arsenic and cadmium are classified as carcinogens linked to urologic cancers.
Most evidence regarding these elements comes from studies of high-level occupational exposure.
The systematic review included cohort and case-control studies, excluding nonhuman and high-level exposure studies.
Study quality was assessed using a modified Newcastle-Ottawa Quality Control Assessment Scale.
Clinical Implications
The findings emphasize the importance of investigating environmental exposures in urologic cancer risk assessment. Clinicians should consider the potential impact of nonessential elements in patient histories and risk evaluations.
Conclusion
This review evaluates the associations between nonessential environmental elements and urologic cancers.
by Zhengyi Deng, Jinhui Li, Renyue Ji, Juan Ramon Delgado, Steve H. L. Yim, Linda Kachuri, Andres Cardenas, Rebecca E. Graff, John T. Leppert, Leslie K. Dennis, Benjamin I. Chung, Marvin E. Langston
