Histopathological Findings in Sleeve Gastrectomy Specimens: Prevalence, Determinants, and Clinical Implications in a Large Brazilian Cohort - Report - MDSpire

Histopathological Findings in Sleeve Gastrectomy Specimens: Prevalence, Determinants, and Clinical Implications in a Large Brazilian Cohort

  • By

  • Marina de Oliveira Menezes

  • Luiz Henrique Bandeira de Andrade Lima Filho

  • Luciana Teixeira de Siqueira

  • José Guido Corrêa de Araujo Júnior

  • Júlia Maria Mendes Lins

  • Álvaro Antônio Bandeira Ferraz

  • June 30, 2026

  • 0 min

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Clinical Report: Histopathological Analysis of Sleeve Gastrectomy Samples

Overview

This study evaluates the histopathological findings in sleeve gastrectomy specimens from 1,475 patients, highlighting the prevalence of gastric lesions and their associations with demographic factors.

Background

Obesity is a significant global health issue associated with various comorbidities, including an increased risk of gastrointestinal cancers. Sleeve gastrectomy is a prevalent bariatric surgical procedure that aids in weight loss and induces metabolic changes.

Data Highlights

No specific numerical data was provided in the source material.

Key Findings

  • 1,475 patients underwent sleeve gastrectomy, with a focus on histopathological analysis.
  • Most specimens exhibited nonspecific inflammatory changes, such as mild gastritis.
  • Helicobacter pylori infection and atrophic gastritis were among the notable findings.
  • The prevalence of premalignant changes varied.
  • Demographic factors, including age and sex, were analyzed for associations with histopathological findings.

Clinical Implications

The study emphasizes the importance of histopathological evaluation of gastric specimens post-sleeve gastrectomy.

Conclusion

The histopathological analysis of sleeve gastrectomy specimens reveals a range of findings.

Related Resources & Content

  1. Janik et al., Obesity Surgery, 2018 -- Assessment of Gastric Tissue Samples Post-Laparoscopic Sleeve Gastrectomy: A Potential Method for Detecting Incidental Pathologies?
  2. Obesity Surgery, 2025 -- Evaluation of Laparoscopic Sleeve Gastrectomy Outcomes with and without Prior Intragastric Balloon Placement: Analyzing Stomach Volume, Histopathological Alterations, Hormonal Changes, and Surgical Results
  3. Obesity Surgery, 2017 -- Outcomes of Sleeve Gastrectomy in Individuals with a BMI of 30 to 35: A Three-Year Follow-Up Study
  4. International Federation for Surgery for Obesity and Metabolic Disorders, 2025 -- Position Statement on the role of Upper Gastrointestinal Endoscopy Before and After Metabolic Bariatric Surgery
  5. Obesity Surgery — An Effective Method for Preoperative Assessment of Sleeve Gastrectomy Challenges
  6. International Federation for Surgery for Obesity and Metabolic Disorders Position Statement on the role of Upper Gastrointestinal Endoscopy Before and After Metabolic Bariatric Surgery
  7. Histopathological Examination of 404 Sleeve Gastrectomy Specimens at a Large UK Center and Systematic Review of the Published Literature - PubMed
  8. Histopathological findings in obese patients undergoing laparoscopic sleeve gastrectomy in the Western region of Saudi Arabia - PubMed
  9. 25053 504..554
  10. https://webfiles.gi.org/links/journals/ACG-Hpylori-Guidelines-Highlights-2024-FINAL.pdf

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