Percutaneous endoscopic interlaminar discectomy vs. percutaneous endoscopic transforaminal discectomy for L5/S1 lumbar disc herniation: a systematic review and meta-analysis of randomized controlled trials - Report - MDSpire

Percutaneous endoscopic interlaminar discectomy vs. percutaneous endoscopic transforaminal discectomy for L5/S1 lumbar disc herniation: a systematic review and meta-analysis of randomized controlled trials

  • By

  • Huatao Chen

  • Cai Cheng

  • July 14, 2026

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Clinical Report: Comparing PEID and PETD for L5/S1 Lumbar Disc Herniation

Overview

This systematic review and meta-analysis evaluated the perioperative efficiency, clinical outcomes, and safety of percutaneous endoscopic interlaminar discectomy (PEID) versus percutaneous endoscopic transforaminal discectomy (PETD) for L5/S1 lumbar disc herniation. Findings indicate that PEID may result in shorter operative times and reduced fluoroscopy frequency.

Background

L5/S1 lumbar disc herniation is a prevalent condition that can lead to significant pain and disability. The choice of surgical approach is critical, as anatomical constraints at this level can affect the efficacy and safety of the procedure.

Data Highlights

OutcomePEIDPETDMean Difference (MD)95% CI
Operative TimeShorterLonger-17.07 min-26.05 to -8.09
Fluoroscopy FrequencyLowerHigher-8.94 counts-11.40 to -6.48
Hospital StayComparableComparable0.38 days-0.36 to 1.12
VAS Leg PainComparableComparableN/AN/A
ODIComparableComparableN/AN/A
ComplicationsComparableComparable0.008-0.019 to 0.035

Key Findings

  • PEID was associated with a significantly shorter operative time compared to PETD.
  • Fluoroscopy frequency was lower in PEID compared to PETD.
  • No significant difference in hospital stay duration between PEID and PETD.
  • VAS leg pain and ODI outcomes were comparable across both surgical approaches.
  • Complications and adverse events did not differ significantly between the two techniques.

Clinical Implications

The choice of procedure should be individualized based on patient-specific anatomical considerations and clinical context.

Conclusion

The findings indicate that PEID may be associated with shorter operative times and reduced fluoroscopy frequency compared to PETD. Further research is warranted to clarify these results given the high heterogeneity observed.

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  8. Brain and Spine | The EANS Guidelines on the Management of Lumbar Disc Hernation | ScienceDirect.com by Elsevier
  9. Full-endoscopic lumbar spine discectomy: in search of the optimal approach—a meta-analysis comparing interlaminar endoscopic lumbar discectomy (IELD) and transforaminal endoscopic lumbar discectomy (TELD) | Neurosurgical Review | Springer Nature Link
  10. Full-endoscopic versus microscopic lumbar discectomy for lumbar disc herniation: a systematic review and meta-analysis of 4,186 cases - PubMed

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