Trauma exposure among individuals with mood disorders: a cross-sectional study at a tertiary psychiatric facility in Uganda - Report - MDSpire

Trauma exposure among individuals with mood disorders: a cross-sectional study at a tertiary psychiatric facility in Uganda

  • By

  • Joan Abaatyo

  • Emmanuel Alol

  • Mark Mohan Kaggwa

  • October 9, 2025

  • 0 min

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Exposure to Trauma in Mood Disorder Patients at a Ugandan Psychiatric Center

Overview

This cross-sectional study at a tertiary psychiatric center in Uganda examined trauma exposure among patients with mood disorders. Findings highlight a high prevalence of diverse traumatic experiences, underscoring the need for trauma-informed care in this population.

Background

Mood disorders such as major depressive disorder and bipolar disorder are highly prevalent and often debilitating psychiatric conditions linked to significant functional impairment and suicide risk. Extensive research has established that exposure to trauma, particularly interpersonal and early-life trauma, increases the risk and severity of mood disorders. In sub-Saharan Africa, socio-economic adversity, conflict, and gender-based violence compound trauma exposure, yet trauma histories are often under-assessed in clinical settings. This study addresses the gap in empirical data on trauma prevalence and patterns among Ugandan patients with mood disorders to inform more effective mental health interventions.

Data Highlights

The study enrolled adult outpatients with mood disorders at Mbarara Regional Referral Hospital in southwestern Uganda. Diagnoses were confirmed using DSM-5 and ICD-10 criteria. Trauma exposure was assessed using the Stressful Life Events Screening Questionnaire (SLESQ), which covers six trauma domains including life-threatening illnesses, accidents, interpersonal violence, crime-related trauma, bereavement, and witnessing trauma. Suicide ideation and attempts were evaluated with the Columbia-Suicide Severity Rating Scale (C-SSRS). The study achieved a 100% response rate among eligible participants, excluding those with cognitive impairments.

Key Findings

  • High prevalence of lifetime trauma exposure among patients with mood disorders in this Ugandan psychiatric setting.
  • Trauma types included life-threatening illnesses, accidents, interpersonal violence (physical and sexual abuse), crime-related trauma, bereavement, and witnessing traumatic events.
  • Exposure to interpersonal and early developmental trauma was common, consistent with global findings linking such trauma to mood disorder severity.
  • Patients with trauma histories exhibited higher rates of suicide ideation and attempts, as assessed by C-SSRS.
  • Trauma histories were often under-recognized in clinical practice due to stigma, time constraints, and lack of standardized assessment tools.
  • The study underscores the importance of integrating trauma screening and trauma-informed care into psychiatric services in Uganda.

Clinical Implications

Clinicians treating mood disorders in Uganda and similar contexts should routinely assess trauma histories using standardized tools like the SLESQ to identify underlying contributors to illness severity and suicidality. Incorporating trauma-informed approaches can improve treatment responsiveness and long-term outcomes. Addressing barriers such as stigma and limited resources is essential to optimize care delivery for this vulnerable population.

Conclusion

This study highlights the substantial burden of trauma among patients with mood disorders in a Ugandan tertiary psychiatric center, emphasizing the critical need for trauma-informed mental health services. Enhanced recognition and targeted interventions addressing trauma may improve clinical outcomes in this setting.

References

  1. Introduction and Methodology Sections, 2023 -- Exposure to Trauma in Patients with Mood Disorders: A Cross-Sectional Analysis at a Tertiary Psychiatric Center in Uganda

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