Correction: Differential infiltration of CD4+ and CD8+ T cells and expression of PD-L1 in paired biopsy and resection specimens of gastric and colorectal adenocarcinomas - Report - MDSpire

Correction: Differential infiltration of CD4+ and CD8+ T cells and expression of PD-L1 in paired biopsy and resection specimens of gastric and colorectal adenocarcinomas

  • By

  • Zi-xuan Wang

  • Chun-mei Zhang

  • Yao-zhen Liu

  • Yu-wei Zhang

  • Shi-jie Tong

  • Qi Liu

  • Duo Deng

  • Yun Pan

  • July 13, 2026

Share

Correction: Variations in CD4+ and CD8+ T cell Infiltration and PD-L1 Expression

Overview

This correction addresses the affiliation error of the first author in the study comparing CD4+ and CD8+ T cell infiltration and PD-L1 expression in gastric and colorectal adenocarcinomas. The original findings remain unchanged.

Background

Gastric and colorectal adenocarcinomas are significant contributors to cancer morbidity and mortality worldwide. This study highlights the importance of accurate sampling and assessment methods in evaluating tumor-infiltrating lymphocytes and PD-L1 expression.

Data Highlights

No numerical data or trial results are provided in the correction notice.

Key Findings

  • The first author's affiliation was corrected from the School of Clinical Medicine to the School of Basic Medical Sciences at Dali University.
  • The study evaluated paired biopsy and resection samples from 38 gastric and 40 colorectal adenocarcinoma patients.
  • Immunohistochemistry was used to assess CD4+ and CD8+ T cell density and PD-L1 expression.
  • Associations with clinicopathological characteristics were explored in the original study.

Clinical Implications

Accurate identification of immune cell infiltration and PD-L1 expression is essential for predicting patient responses to immunotherapy.

Conclusion

This correction clarifies the authorship details while maintaining the integrity of the original research findings on immune cell dynamics in gastric and colorectal adenocarcinomas.

Related Resources & Content

  1. Wang Z, Zhang C, Liu Y, et al., Frontiers in Oncology, 2026 -- Correction: Variations in CD4+ and CD8+ T cell Infiltration and PD-L1 Expression
  2. Gastric Cancer — Significance of PD-1 Expressing CD8 T-Cells in the Context of Gastric Cancer
  3. Gastric Cancer — Enhanced Scoring of PD-L1 in Gastric Carcinoma
  4. Gastric Cancer — Simultaneous Targeting of PD-1/PD-L1, Lag-3, and Tim-3 Pathways Enhances Antitumor Immune Responses in Coculture Models of Gastric Cancer T Cells
  5. Significance of PD-1 Expressing CD8 T-Cells in the Context of Gastric Cancer
  6. Enhanced Scoring of PD-L1 in Gastric Carcinoma
  7. Immunotherapy and Targeted Therapy for Advanced Gastroesophageal Cancer: ASCO Guideline Update
  8. Relationship between programmed cell death ligand 1 expression and the number of biopsy specimens in advanced gastric cancer
  9. Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
  10. ‘Triple-Punch’ Combo Therapy Slows Progressions of Some Metastatic Colorectal Cancers - ASCO
  11. Comparative Analysis of Tumor‐Immune Microenvironment Diversity Among Biopsy, Resection, and Metastatic Colorectal Cancer Specimens - PMC
  12. Prognostic role of tumor-infiltrating lymphocytes in gastric cancer: A systematic review and meta-analysis - PubMed

Original Source(s)

Related Content