Intraoperative Lidocaine Infusion Therapy and Neurophysiological Monitoring in Adolescents Undergoing Idiopathic Scoliosis Correction: A Supplemental Analysis of a Prospective Study - Report - MDSpire
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Evaluation of Intraoperative Lidocaine Administration and Neurophysiological Monitoring in Adolescents Undergoing Surgery for Idiopathic Scoliosis: An Additional Analysis of a Prospective Study

  • By

  • Katherine L. Mason

  • Tabrez Hussein

  • Miku Wake

  • Nicholas West

  • Gillian Lauder

  • June 18, 2026

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Clinical Report: Evaluation of Intraoperative Lidocaine and Neurophysiological Monitoring

Overview

This study investigates the effects of intravenous lidocaine infusion therapy (IVLT) on intraoperative neurophysiological monitoring (IONM) during posterior spinal instrumentation and fusion (PSIF) in adolescents with idiopathic scoliosis.

Background

Intraoperative neurophysiological monitoring is crucial during PSIF to prevent neurological damage. Anesthetic agents can influence IONM measurements, making it essential to ensure their safe use. This study builds on previous research by employing a randomized controlled trial design to assess the impact of IVLT on IONM.

Data Highlights

GroupReportable IONM Events
IVLT (n=23)8 (35%)
Control (n=21)7 (33%)

Key Findings

  • No significant difference in reportable IONM events between IVLT and control groups.
  • Motor evoked potential amplitudes showed no clinically meaningful reduction in both upper and lower limbs.
  • Somatosensory evoked potential amplitudes did not differ significantly between groups.
  • Further research is suggested to corroborate these findings.

Clinical Implications

The study supports the safe use of IVLT during PSIF without compromising IONM, which is vital for monitoring neurological function. Clinicians can consider incorporating IVLT into multimodal analgesia protocols for adolescents undergoing this surgery.

Conclusion

Further studies are warranted to validate these findings.

Related Resources & Content

  1. Mason et al., Pediatric Anesthesia, 2026 -- Intraoperative Lidocaine Infusion Therapy and Neurophysiological Monitoring in Adolescents Undergoing Idiopathic Scoliosis Correction: A Supplemental Analysis of a Prospective Study
  2. Drugs - Real World Outcomes, 2020 -- Efficacy of Intravenous Lidocaine in Managing Acute Pain: A Retrospective Analysis from One Institution
  3. Techniques in Coloproctology, 2018 -- Intravenous Lidocaine Infusion for Managing Postoperative Pain and Enhancing Recovery in Adult Patients
  4. Surgical Endoscopy, 2024 -- The Use of Intravenous Lidocaine Reduces the Rate of Sedation-Related Adverse Events in Elderly Patients Undergoing ERCP: Results from a Randomized Controlled Trial
  5. SRS -- Intraoperative Neurophysiological Monitoring Information Statement
  6. Intraoperative Neurophysiological Monitoring During Surgery for Intramedullary Spinal Cord Lesions: Procedures, Setup, and Results
  7. SRS
  8. Intraoperative Lidocaine Infusion Therapy and Neurophysiological Monitoring in Adolescents Undergoing Idiopathic Scoliosis Correction: A Supplemental Analysis of a Prospective Study - Mason - Pediatric Anesthesia - Wiley Online Library
  9. Effects of Adjunct Analgesics and Novel Anesthetic Agents on Intraoperative Neuromonitoring: A Scoping Review - PubMed

Original Source(s)

Intraoperative Lidocaine Infusion Therapy and Neurophysiological Monitoring in Adolescents Undergoing Idiopathic Scoliosis Correction: A Supplemental Analysis of a Prospective Study

  • by Katherine L. Mason, Tabrez Hussein, Miku Wake, Nicholas West, Gillian Lauder

  • June 18, 2026

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