Validation of the Chinese version of Morningness-Eveningness Questionnaire for screening delayed sleep-wake phase disorder with bipolar disorder among Han Chinese population - Report - MDSpire

Validation of the Chinese version of Morningness-Eveningness Questionnaire for screening delayed sleep-wake phase disorder with bipolar disorder among Han Chinese population

  • By

  • Ting Yang

  • Yuchen Lin

  • Tong Li

  • Zhaoyu Gan

  • April 30, 2026

  • 0 min

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Clinical Report: Assessment of the Chinese Adaptation of the MEQ for DSWPD

Overview

Expand on the implications of the MEQ's internal consistency and the significance of the score differences.

Background

Delayed sleep-wake phase disorder (DSWPD) is frequently observed in patients with bipolar disorder (BD), impacting their overall health and treatment outcomes. Accurate screening tools are essential for timely diagnosis and management of DSWPD, particularly in diverse populations. The validation of the MEQ in the Han Chinese community addresses a critical gap in the assessment of sleep disorders in this demographic.

Data Highlights

MeasureBD with DSWPDBD without DSWPDHealthy Controls
MEQ Score36.85 ± 6.4047.44 ± 7.3947.96 ± 7.28
Internal Consistency (Cronbach’s α)0.758
Split-Half Reliability0.719
Retest Reliability0.661
AUC0.867

Key Findings

  • The MEQ showed an internal consistency of 0.758, indicating good reliability.
  • BD patients with DSWPD had significantly lower MEQ scores compared to those without DSWPD and healthy controls (p<0.001).
  • The optimal cut-off score for identifying DSWPD was determined to be 43, with a sensitivity of 0.83 and specificity of 0.75.
  • Exploratory factor analysis revealed three factors contributing to the MEQ scale.
  • The area under the ROC curve for the MEQ was 0.867, indicating strong diagnostic performance.

Clinical Implications

The validated Chinese version of the MEQ can be effectively utilized in clinical settings to screen for DSWPD among bipolar disorder patients, facilitating early diagnosis and intervention. This tool's accessibility and reliability make it a valuable addition to the assessment of sleep disorders in the Han Chinese population.

Conclusion

The study confirms that the Chinese version of the MEQ is a valid and reliable tool for screening DSWPD in bipolar disorder patients. This advancement supports improved clinical practices in managing sleep disorders within this population.

References

  1. Frontiers, 2026 -- Validation of the Chinese version of Morningness-Eveningness Questionnaire for Screening Delayed Sleep-Wake Phase Disorder with Bipolar Disorder among Han Chinese population
  2. BMC Psychiatry (Springer) — A Biomarker for Niacin-Induced Flushing Exhibiting Disorder-Specific Multivariate Associations in Adolescent Unipolar and Bipolar Depression
  3. BMC Psychiatry (Springer) — Comparative Analysis of Biochemical Metabolism and Cognitive Abilities in Bipolar I versus Bipolar II Disorder
  4. BMC Psychiatry (Springer) — Childhood Trauma's Influence on Depressive Symptoms in Adolescents with Bipolar Disorder: The Role of Sleep Disturbance as a Mediator
  5. Sleep abnormalities in bipolar disorders across mood phases: A systematic review and meta-analysis - ScienceDirect
  6. BMC Psychiatry (Springer) — Alterations in Prefrontal Dynamics Over Time During Emotional Association in Depression: An fNIRS Case-Control Investigation
  7. Research Agenda
  8. Sleep abnormalities in bipolar disorders across mood phases: A systematic review and meta-analysis - ScienceDirect
  9. Frontiers | Validation of the Chinese version of Morningness-Eveningness Questionnaire for Screening Delayed Sleep-Wake Phase Disorder with Bipolar Disorder among Han Chinese population

Original Source(s)

Validation of the Chinese version of Morningness-Eveningness Questionnaire for screening delayed sleep-wake phase disorder with bipolar disorder among Han Chinese population

  • by Ting Yang, Yuchen Lin, Tong Li, Zhaoyu Gan

  • April 30, 2026

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