Case Report: A four-stage diagnostic cascade: from coronary stents to pancreatic cancer in a patient with recurrent chest pain - Report - MDSpire

Case Report: A four-stage diagnostic cascade: from coronary stents to pancreatic cancer in a patient with recurrent chest pain

  • By

  • Tao Lin

  • Ziyi Huang

  • Xiahui Huang

  • June 29, 2026

  • 0 min

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Clinical Report: A Four-Step Diagnostic Journey from Coronary Stenting to Cancer

Overview

This case study illustrates the diagnostic challenges faced when a patient with recurrent chest pain underwent coronary stenting, only to later reveal pancreatic cancer.

Background

Chest pain is a common presentation in emergency settings, often leading to a focus on cardiac causes. However, non-cardiac origins, particularly intra-abdominal pathologies like pancreatic cancer, can mimic cardiac symptoms, complicating diagnosis.

Data Highlights

No numerical data or trial data presented in the article.

Key Findings

  • The patient initially presented with recurrent chest pain, leading to coronary stenting.
  • Subsequent evaluations revealed acute pancreatitis and ultimately pancreatic uncinate process carcinoma.
  • Laboratory findings evolved over multiple hospitalizations.
  • Chest pain can originate from non-cardiac causes.
  • Misdiagnosis can occur due to cognitive anchoring on cardiac conditions.

Clinical Implications

Clinicians should consider non-cardiac causes of chest pain in patients with a history of coronary artery disease.

Conclusion

This case highlights the potential for serious underlying conditions that may be overlooked.

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- Case Report: Metastatic pancreatic ductal adenocarcinoma initially masked by multiple gastroduodenal ulcers with apparent endoscopic healing: a diagnostic pitfall
  2. Frontiers in Oncology, 2026 -- Metachronous cholangiocarcinoma following pancreaticoduodenectomy and the potential role of a migrated pancreaticojejunal stent: a case report and review of the literature
  3. Frontiers in Surgery, 2026 -- Case Report: Unexpected LAMS obstruction following successful EUS-BD in a patient with pancreatic carcinoma
  4. The New Gastroenterologist, 2025 -- Evaluation Strategies for Rare Cancer Screening
  5. JACC, 2025 -- 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes
  6. Noncardiac (GERD) Chest Pain: Location, Symptoms, Treatment
  7. 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | JACC

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