Translation, cultural adaptation, and psychometric validation of the Arabic version of the university of Washington quality-of-life questionnaire in Jordanian head-and-neck cancer patients - Report - MDSpire

Translation, cultural adaptation, and psychometric validation of the Arabic version of the university of Washington quality-of-life questionnaire in Jordanian head-and-neck cancer patients

  • By

  • Da’ad Abdel-Hay

  • Osama Abdelhay

  • Ra’ad Al Sunna

  • Mutaz A. Al Tamimi

  • July 15, 2026

Share

Cultural Adaptation, Translation, and Psychometric Evaluation of the Arabic UW-QoL

Overview

This study translated and validated the Arabic version of the UW-QoL v4 for head and neck cancer patients in Jordan. The Arabic UW-QoL v4 demonstrated good internal consistency and test-retest reliability.

Background

Assessing health-related quality of life (HR-QoL) is essential for understanding the impact of head and neck cancer (HNC) on patients' lives. The University of Washington Quality of Life Questionnaire (UW-QoL) is a recognized tool for evaluating HR-QoL in HNC patients, but its applicability in non-English speaking populations has been limited. This study addresses the need for a culturally adapted and validated Arabic version of the UW-QoL for Jordanian patients.

Data Highlights

MeasureResult
Cronbach’s alpha (total scale)0.89
Cronbach’s alpha (physical-function subscale)0.86
Spearman-Brown (socio-emotional subscale)0.86
Test-retest reliability (ICC)0.95
Floor effects4.1% to 14.3%
Ceiling effects26.5% to 50.0%
Mann-Whitney U test (early vs advanced tumor stage)p = 0.0025

Key Findings

  • The Arabic UW-QoL v4 showed good internal consistency with a Cronbach’s alpha of 0.89.
  • Test-retest reliability was excellent, with an ICC of 0.95 for the total score.
  • Exploratory PCA indicated a two-component solution with eigenvalues of 5.67 and 1.06.
  • Floor effects ranged from 4.1% to 14.3%, while ceiling effects ranged from 26.5% to 50.0%.
  • Higher total scores were observed in patients with early-stage tumors compared to advanced stages (p = 0.0025).

Clinical Implications

The validated Arabic UW-QoL v4 can be utilized in clinical settings to assess HR-QoL among Jordanian HNC patients.

Conclusion

The Arabic version of the UW-QoL v4 is a reliable and culturally appropriate instrument for assessing quality of life in Jordanian head and neck cancer patients.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Author(s)/Org, Source, Year -- Title
  3. Author(s)/Org, Source, Year -- Title
  4. Author(s)/Org, Source, Year -- Title
  5. COSMIN reporting guideline for studies on measurement properties of patient‑reported outcome measures: version 2.0 - PubMed
  6. Primary results for the phase III trial of Toxicity Reduction using Proton Beam Therapy for Oropharyngeal Cancer (TORPEdO; CRUK/18/010) - ScienceDirect
  7. Responsiveness and clinical utility of patient-reported outcome instruments in head and neck cancer: a systematic review - PubMed
  8. COSMIN reporting guideline for studies on measurement properties of patient‑reported outcome measures: version 2.0 - PubMed
  9. Primary results for the phase III trial of Toxicity Reduction using Proton Beam Therapy for Oropharyngeal Cancer (TORPEdO; CRUK/18/010) - ScienceDirect
  10. Responsiveness and clinical utility of patient-reported outcome instruments in head and neck cancer: a systematic review - PubMed

Original Source(s)

Related Content