Kaposiform Hemangioendothelioma in the Nasal Region: An Uncommon Condition in an Unusual Site—A Case Study and Literature Review
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By
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Feras Alkholaiwi
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Ji Yun Choi
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May 13, 2026
Clinical Report: Kaposiform Hemangioendothelioma in the Nasal Region
Overview
This report presents a rare case of kaposiform hemangioendothelioma (KHE) in a 59-year-old female, highlighting its unusual presentation in the nasal region. The patient underwent successful endoscopic resection with no postoperative complications and no signs of recurrence after five months.
Background
Kaposiform hemangioendothelioma is a rare vascular neoplasm that typically presents in infancy and early childhood, but cases in adults are documented. It is characterized by local aggressiveness and potential for lymphatic dissemination, making early diagnosis and management crucial. The occurrence of KHE in the head and neck region, particularly the nasal cavity, is uncommon, necessitating awareness among healthcare professionals.
Data Highlights
No numerical data available in the article.
Key Findings
- The patient presented with right-sided nasal obstruction and epistaxis.
- Contrast-enhanced CT revealed an enhancing mass from the right inferior turbinate.
- Histopathological evaluation confirmed the diagnosis of kaposiform hemangioendothelioma.
- The tumor was positive for CD34 and CD31 on immunohistochemical assessment.
- No recurrence was noted after five months of follow-up.
Clinical Implications
Healthcare professionals should consider kaposiform hemangioendothelioma in differential diagnoses for nasal masses, especially in adults presenting with nasal obstruction and epistaxis. Early identification and appropriate surgical intervention can lead to favorable outcomes without complications.
Conclusion
This case underscores the importance of recognizing kaposiform hemangioendothelioma in atypical locations and highlights the successful management of this rare neoplasm through endoscopic resection.
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Based on findings from:
Nasal kaposiform hemangioendothelioma: a rare disease in a rare location—a review article with a case report
Feras Alkholaiwi, Ji Yun Choi. Frontiers In Surgery, 2026.
https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2026.1728160/full
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