Effectiveness of digital health interventions on antiretroviral therapy adherence among people living with HIV in India: A systematic review with an RCT-only meta-analysis - Report - MDSpire

Effectiveness of digital health interventions on antiretroviral therapy adherence among people living with HIV in India: A systematic review with an RCT-only meta-analysis

  • By

  • Vaibhav Gupta

  • Vishal Deo

  • Barnali Deka

  • Garima Jain

  • Sunny Yadav

  • Sanghamitra Pati

  • June 15, 2026

  • 0 min

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Clinical Report: Efficacy of Digital Health Strategies on ART Adherence in India

Overview

This systematic review and meta-analysis evaluate the effectiveness of digital health strategies in enhancing adherence to antiretroviral therapy (ART) among HIV-positive individuals in India. The findings indicate that digital interventions can significantly improve adherence rates, which is crucial for achieving viral suppression and reducing HIV transmission.

Background

Adherence to ART is essential for the effective management of HIV, as it directly impacts viral load and transmission rates. In India, despite improvements in ART coverage, adherence remains suboptimal, with various barriers affecting patient engagement. Digital health strategies present a promising avenue to address these challenges and improve treatment outcomes.

Data Highlights

No specific numerical data provided in the source material.

Key Findings

  • Digital health interventions, including SMS reminders and mobile apps, have shown effectiveness in improving ART adherence.
  • Adherence rates among HIV-positive individuals in India are reported to be below the optimal threshold of 95%.
  • Barriers to adherence include forgetfulness, stigma, and lack of social support.
  • Real-time monitoring tools can enhance adherence by providing timely reminders and support.
  • Improved adherence is associated with better viral suppression outcomes.

Clinical Implications

Healthcare providers should consider integrating digital health strategies into routine care for HIV-positive patients to enhance adherence to ART. Addressing barriers to adherence through personalized digital interventions can lead to better health outcomes and reduced transmission rates.

Conclusion

Digital health strategies represent a valuable tool in improving ART adherence among HIV-positive individuals in India. Continued research and implementation of these interventions are essential for achieving public health goals in HIV management.

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- The role of digital health interventions for adults with tuberculosis: a network meta-analysis of randomized controlled trials
  2. The Journal of Infectious Diseases, 2026 -- Adaptive Trial Designs: Connecting Clinical Research and Practice in Infectious Disease Management
  3. Journal of Medical Internet Research (JMIR), 2026 -- A Stepped Care Approach to Promoting Engagement in a Digital Health Intervention: Secondary Analysis of a Randomized Controlled Trial
  4. Journal of Medical Internet Research (JMIR), 2026 -- Effectiveness of Digital Health Interventions to Improve Self-Care in Patients With Chronic Diseases: Systematic Review and Meta-Analysis of Randomized Controlled Trials
  5. Adherence support - WHO guideline on HIV service delivery, 2025
  6. The Effect of Real-Time Medication Monitoring-Based Digital Adherence Tools on Adherence to Antiretroviral Therapy and Viral Suppression in People Living With HIV: A Systematic Literature Review and Meta-Analysis - PMC
  7. Adherence support - WHO guideline on HIV service delivery - NCBI Bookshelf
  8. The Effect of Real-Time Medication Monitoring-Based Digital Adherence Tools on Adherence to Antiretroviral Therapy and Viral Suppression in People Living With HIV: A Systematic Literature Review and Meta-Analysis - PMC
  9. https://naco.mohfw.gov.in/sites/default/files/CSC%20Operational%20Guidelines_Latest.pdf

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