Applications of artificial intelligence in cardiovascular risk detection and prediction among adults with obesity: a scoping review - Report - MDSpire

Applications of artificial intelligence in cardiovascular risk detection and prediction among adults with obesity: a scoping review

  • By

  • Mario Andrés Torres Torres

  • Mariana González Garcés

  • Jerónimo Cárdenas Montoya

  • Valeria Concha Fernández

  • Erwin Hernando Hernández Rincón

  • May 12, 2026

  • 0 min

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Clinical Report: Utilization of Artificial Intelligence for Cardiovascular Risk in Obesity

Overview

This scoping review evaluates the application of artificial intelligence (AI) in identifying and predicting cardiovascular risk in obese adults. Findings indicate that while AI shows promise, challenges such as methodological heterogeneity and limited external validation hinder its clinical implementation.

Background

Obesity significantly elevates cardiovascular risk, which is a leading cause of mortality globally. Traditional risk prediction tools often fail to account for the unique metabolic complexities associated with obesity. The integration of AI into cardiovascular risk assessment may enhance detection and prediction capabilities, addressing these limitations.

Data Highlights

Study TypeNumber of StudiesCommon AI MethodsFocus Areas
Retrospective30Random Forest, Gradient BoostingRisk Stratification, Disease Detection

Key Findings

  • Thirty studies were included, primarily retrospective and with heterogeneous populations.
  • Tree-based ensemble methods, especially Random Forest and gradient boosting, were the most commonly used AI techniques.
  • Outcomes focused mainly on cardiovascular risk stratification and disease detection.
  • Prediction of incident cardiovascular events and mortality was less frequently addressed.
  • External validation of AI models was rarely reported, and model performance was generally moderate.

Clinical Implications

Healthcare professionals should consider the potential of AI as a complementary tool for cardiovascular risk assessment in obese patients. However, the current limitations in methodology and validation must be acknowledged when interpreting AI-generated risk predictions.

Conclusion

AI has the potential to enhance cardiovascular risk assessment in obese adults, but further research is needed to standardize methodologies and validate outcomes for clinical application.

Related Resources & Content

  1. European Journal of Preventive Cardiology, 2023 -- Beyond traditional scores: a critical look at machine learning approaches in cardiovascular risk assessment
  2. npj Digital Medicine, 2025 -- Artificial intelligence-enabled analysis of handheld single-lead electrocardiograms to predict incident atrial fibrillation: an analysis of the VITAL-AF randomized trial
  3. Obesity and Endocrinology, 2023 -- Revolutionizing Obesity Treatment through Artificial Intelligence: Tailoring Approaches and Future Directions
  4. Obesity Surgery, 2022 -- Recent Uses of Artificial Intelligence in the Field of Bariatric Surgery
  5. American Heart Association, 2025 -- The PREVENTTM equations can improve, personalize care for adults with high BP
  6. American College of Cardiology, 2025 -- 2025 Concise Clinical Guidance: An ACC Expert Consensus Statement on Medical Weight Management for Optimization of Cardiovascular Health
  7. New guidance offered for responsible AI use in health care
  8. The PREVENTTM equations can improve, personalize care for adults with high BP | American Heart Association
  9. 2025 Concise Clinical Guidance: An ACC Expert Consensus Statement on Medical Weight Management for Optimization of Cardiovascular Health - American College of Cardiology

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