Case Report: Cotard’s syndrome associated with suicide attempt-related delirium - Report - MDSpire

Case Report: Cotard’s syndrome associated with suicide attempt-related delirium

  • By

  • Richárd Flach

  • Júlia Éva Varga

  • Róbert Herold

  • Vita Bányavölgyi

  • Péter Osvath

  • Sándor Fekete

  • Viktor Voros

  • Tamás Tényi

  • July 3, 2026

  • 0 min

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Clinical Report: Cotard’s Syndrome Linked to Delirium Following Suicide Attempt

Overview

This case study presents an 88-year-old man who developed Cotard’s syndrome characterized by nihilistic delusions following a suicide attempt in the context of severe depression. The interplay of delirium, depressive symptoms, and neurocognitive impairment is highlighted.

Background

Cotard’s syndrome is a rare but serious condition often associated with severe psychiatric disorders, particularly depression. It is characterized by delusions of non-existence and can lead to significant self-neglect and suicidal behavior.

Data Highlights

No numerical data or trial data were provided in the source material.

Key Findings

  • An 88-year-old man with no prior psychiatric treatment developed Cotard’s syndrome after a suicide attempt.
  • His clinical presentation included nihilistic beliefs, confusion, and depressive symptoms.
  • Fluctuating consciousness and neurocognitive impairment were noted during his hospitalization.
  • Treatment with risperidone, mirtazapine, and supportive psychotherapy led to gradual resolution of symptoms.
  • The case underscores the importance of differential diagnosis in older adults presenting with nihilistic delusions.

Clinical Implications

This case emphasizes the need for careful assessment of older patients exhibiting nihilistic delusions, particularly in the context of severe depression and delirium.

Conclusion

The complex interplay of delirium, severe depression, and neurocognitive vulnerability can lead to the emergence of Cotard’s syndrome.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Frontiers in Psychiatry — Dissociative amnesia with fugue following a suicide attempt: a rare clinical intersection of identity loss and suicidal ambivalence: a case report
  3. BMC Psychiatry (Springer) — Insights into Catatonia with and without Delirium in a Lebanese Tertiary Care Setting: A Retrospective Analysis of 36 Cases on the Consultation-Liaison Psychiatry Service
  4. Frontiers in Psychiatry — Postpartum delirious mania in a patient with diagnosis of bipolar disorder after cesarean delivery: a case report
  5. Critical Care (Springer) — Association between isolation room admission in intensive care units and long-term psychiatric disorders: a nationwide cohort study
  6. Cotard syndrome: Pathology review | European Psychiatry | Cambridge Core
  7. VA/DoD Clinical Practice Guideline for Assessment and Management of Patients at Risk for Suicide
  8. Recommendations | Depression in adults: treatment and management | Guidance | NICE

Original Source(s)

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