Latent transition analysis of resilience in breast cancer patients and its association with sense of meaning in life: a longitudinal follow - up study - Report - MDSpire

Latent transition analysis of resilience in breast cancer patients and its association with sense of meaning in life: a longitudinal follow - up study

  • By

  • Huiping Tian

  • Yue Wang

  • Song Guo

  • June 11, 2026

  • 0 min

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Longitudinal Latent Transition Analysis of Resilience Among Breast Cancer Patients

Overview

This study examines the changes in psychological resilience among breast cancer patients over time and its correlation with their sense of meaning in life. Findings indicate significant transitions between resilience categories and highlight the need for psychological interventions.

Background

Breast cancer is a prevalent malignancy among women, often leading to psychological distress that can impact life meaning. Understanding the dynamics of resilience and its relationship with life meaning is crucial for enhancing patient adaptation and overall well-being. This study addresses a gap in the literature by employing a longitudinal approach to assess these constructs.

Data Highlights

GroupPercentage
Persistent Low-Risk Group (C2)31.48%
Persistent High-Risk Group (C1)25.25%
Resilience Enhancing Group38.63%
Resilience Decline Group5.64%

Key Findings

  • Two latent profile categories of psychological resilience were identified: low (C1) and high (C2).
  • 31.48% of patients remained in the high resilience group (C2) over time.
  • 38.63% of patients transitioned from the high resilience group (C1) to the low resilience group (C2).
  • Multivariate logistic regression indicated increased risk of low life meaning in the persistent high-risk group (OR = 9.488).
  • Continuous psychological intervention is necessary to enhance life meaning among breast cancer patients.

Clinical Implications

The findings suggest that healthcare providers should monitor psychological resilience in breast cancer patients and implement timely interventions. Enhancing the sense of meaning in life may improve overall psychological outcomes and adaptation to the disease.

Conclusion

The study underscores the significant relationship between resilience and life meaning in breast cancer patients, emphasizing the importance of early identification and intervention.

Related Resources & Content

  1. Frontiers in Psychiatry, 2026 -- Patterns and predictors of cognitive function and post-traumatic growth in cancer patients: a latent profile analysis
  2. BMC Psychiatry, 2025 -- Meaning in life among Norwegian outpatients with personality disorders: a cross-sectional study
  3. Journal of Medical Internet Research, 2026 -- Time-Dynamic AI Models to Predict Quality of Life in Patients With Breast Cancer: Development and Validation Study Using the EORTC BALANCE Cohort
  4. Frontiers in Psychiatry, 2026 -- Associations between fear of cancer recurrence and post-traumatic growth in patients with primary liver cancer: a latent profile analysis and mediation analysis
  5. NCCN Guidelines® Insights: Distress Management, Version 1.2026 - PubMed
  6. Frontiers, 2026 -- Comparison of the effects of cognitive-supportive-relaxation multimodal psychosocial intervention on fear of cancer recurrence and psychological resilience in breast cancer patients: a network meta-analysis based on randomized controlled trials
  7. NCCN Guidelines® Insights: Distress Management, Version 1.2026 - PubMed
  8. Frontiers | Comparison of the effects of cognitive-supportive-relaxation multimodal psychosocial intervention on fear of cancer recurrence and psychological resilience in breast cancer patients: a network meta-analysis based on randomized controlled trials

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