Reliability and readability of Artificial Intelligence generated information on acute cholecystitis: A comparative analysis - Report - MDSpire
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Assessment of the Trustworthiness and Comprehensibility of AI-Generated Content on Acute Cholecystitis: A Comparative Study

  • By

  • Mabel Lucero Olarte Jurado

  • Natalia Pimiento Blanco

  • María José Prieto Otero

  • Laura Sofía Rivera González

  • Miguel Enrique Ochoa Vera

  • Jaime Fernando Barajas

  • Cristian Orlando Porras Bueno

  • August 11, 2026

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Clinical Report: Assessment of AI-Generated Content on Acute Cholecystitis

Overview

This study evaluates the reliability and readability of AI-generated information on acute cholecystitis from ChatGPT®, Gemini®, and Perplexity® in English and Spanish.

Background

Acute cholecystitis is a common surgical condition and a leading cause of upper abdominal emergencies, primarily due to gallstones. The increasing use of AI language models for medical information necessitates an assessment of their reliability and clarity.

Data Highlights

No numerical data or trial data were provided in the source material.

Key Findings

  • The study assessed AI-generated responses from ChatGPT®, Gemini®, and Perplexity® regarding acute cholecystitis.
  • Responses were evaluated for reliability and readability in both English and Spanish.
  • The research adhered to STROBE guidelines and was approved by an ethics committee.
  • A total of 42 responses were generated based on seven standardized clinical questions.
  • The study highlights the variability in the quality of AI-generated medical information.

Clinical Implications

Healthcare professionals should critically evaluate AI-generated medical information before use in clinical practice. The findings suggest that while AI tools can provide information, their reliability and clarity may vary significantly.

Conclusion

The study underscores the importance of assessing the quality of AI-generated content in medical contexts, particularly for conditions like acute cholecystitis. Ongoing evaluation is necessary as AI tools continue to evolve.

Related Resources & Content

  1. Surgical Endoscopy, 2024 -- Evaluating the Quality and Content of AI-Generated Medical Information on Appendicitis
  2. Surgical Endoscopy, 2025 -- Employing artificial intelligence to simulate expert panel assessments of cholecystitis severity
  3. Updates in Surgery, 2024 -- Exploring the Future of Laparoscopic Cholecystectomy with Artificial Intelligence: A Comprehensive Review
  4. Surgical Endoscopy, 2024 -- Creation of an AI System to Identify Intraoperative Scarring During Laparoscopic Cholecystectomy for Cholecystitis
  5. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos) - PubMed
  6. The optimal timing of laparoscopic cholecystectomy for acute cholecystitis according to symptom onset and patient admission: a meta-analysis of randomised controlled trials - PubMed
  7. Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high risk patients (CHOCOLATE): multicentre randomised clinical trial | The BMJ
  8. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos) - PubMed
  9. The optimal timing of laparoscopic cholecystectomy for acute cholecystitis according to symptom onset and patient admission: a meta-analysis of randomised controlled trials - PubMed
  10. Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high risk patients (CHOCOLATE): multicentre randomised clinical trial | The BMJ

Original Source(s)

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