Epidemiological patterns and risk profiling of hospital acquired venous thromboembolism in a tertiary medical center in eastern China: a retrospective cohort study (2023–2024) - Report - MDSpire

Epidemiological patterns and risk profiling of hospital acquired venous thromboembolism in a tertiary medical center in eastern China: a retrospective cohort study (2023–2024)

  • By

  • Zheng Yang

  • Jie Qin

  • July 1, 2026

  • 0 min

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Epidemiological Trends and Risk Assessment of Hospital-Acquired VTE

Overview

This study investigates the epidemiological patterns and risk factors of hospital-acquired venous thromboembolism (HA-VTE) in a tertiary care facility over two years.

Background

Hospital-acquired venous thromboembolism (HA-VTE) is a significant cause of morbidity and mortality among hospitalized patients. Understanding the epidemiological trends and risk factors is essential for improving patient safety.

Data Highlights

ParameterValue
Total HA-VTE Cases393
Isolated HA-DVT308
Isolated HA-PE61
Concomitant HA-DVT and HA-PE24

Key Findings

  • 393 inpatients diagnosed with HA-VTE during the study period.
  • 308 patients had isolated hospital-acquired deep vein thrombosis (HA-DVT).
  • 61 patients had isolated hospital-acquired pulmonary embolism (HA-PE).
  • Risk factors included older age, malignancy, trauma, ICU stay, and major surgery.
  • Departments with the highest incidence included Neurosurgery, ICU, and Orthopedics.
  • Patients with HA-VTE experienced longer hospital stays and higher mortality rates.

Clinical Implications

Clinicians should enhance VTE risk assessment and management, particularly for postoperative, infected, and critically ill patients. Tailored prophylaxis strategies are necessary to address the identified risk factors and reduce mortality associated with HA-VTE.

Conclusion

The study emphasizes the need for targeted prevention strategies for HA-VTE, particularly in high-risk surgical populations. Understanding the interplay of risk factors can guide clinical practice in managing and preventing HA-VTE.

Related Resources & Content

  1. Intensive Care Medicine, 2022 -- Patterns and Contributing Factors for the Underuse of Early Thromboprophylaxis in ICUs Across Australia and New Zealand from 2009 to 2020
  2. Clinical Research in Cardiology, 2019 -- Trends Over Time in the Treatment and Outcomes of Pulmonary Embolism: Insights from a Single-Center Study
  3. Infection, 2021 -- Trends and Species Distribution of Bloodstream Infections in a Tertiary Care Facility in China from 2010 to 2019
  4. ISTH 2024 -- Hospital-acquired venous thromboembolism (HA-VTE) Overview
  5. NICE, 2024 -- Overview | Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism
  6. Blood Cancer Journal — Essential Thrombocythemia Among Classic Myeloproliferative Neoplasms Exhibits the Highest Venous Thromboembolism Risk During COVID-19
  7. ISTH 2024
  8. Overview | Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism | Guidance | NICE
  9. Rivaroxaban for Thromboprophylaxis in Acutely Ill Medical Patients | New England Journal of Medicine

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