Chromoblastomycosis caused by Fonsecaea pedrosoi: a case report and literature review - Report - MDSpire

Chromoblastomycosis caused by Fonsecaea pedrosoi: a case report and literature review

  • By

  • Yuyun Wang

  • Lu Wang

  • Zhen Li

  • Yuanqing Qu

  • Yuan Liu

  • May 28, 2026

  • 0 min

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Clinical Report: A Case Study and Literature Review on Chromoblastomycosis Induced by Fonsecaea pedrosoi

Overview

This report details a case of chromoblastomycosis caused by Fonsecaea pedrosoi in an immunocompromised patient. The findings emphasize the challenges in diagnosis and the importance of timely intervention to improve patient outcomes.

Background

Chromoblastomycosis (CBM) is a chronic fungal infection primarily caused by dematiaceous fungi, notably Fonsecaea species. The disease is often misdiagnosed due to its non-specific clinical manifestations, which can lead to delayed treatment and complications. Understanding the clinical characteristics and diagnostic challenges of CBM is crucial, especially in immunocompromised patients who may experience more severe disease progression.

Data Highlights

No numerical data or trial data available in the article.

Key Findings

  • Chromoblastomycosis is often misdiagnosed due to its diverse clinical manifestations.
  • Immunocompromised patients are at higher risk for prolonged disease and slow recovery.
  • Accurate diagnosis requires mycological, histopathological, and molecular examinations.
  • Empiric antifungal treatments may be ineffective without proper diagnosis.
  • Awareness of CBM is essential for improving public health outcomes.

Clinical Implications

Healthcare professionals should maintain a high index of suspicion for chromoblastomycosis in patients with chronic skin lesions, especially in immunocompromised individuals. Early and accurate diagnosis is critical to prevent complications and improve treatment outcomes.

Conclusion

The case underscores the importance of recognizing chromoblastomycosis in clinical practice and highlights the need for improved diagnostic protocols to facilitate timely treatment.

Related Resources & Content

  1. CDC, Chromoblastomycosis Basics, 2023 -- Chromoblastomycosis Basics
  2. Open Forum Infectious Diseases, Unmasking Lomentospora prolificans: A Case Study of Fungemia with Diagnostic Challenges, 2023 -- Unmasking Lomentospora prolificans
  3. Infection, Fusariosis Dissemination Following Allogeneic Hematopoietic Stem Cell Transplantation: A Case Study, 2023 -- Fusariosis Dissemination
  4. Open Forum Infectious Diseases, Broadening the Scope of Epidemiology: A Case Report of Pulmonary Illness Linked to Acrophialophora angustiphialis, 2023 -- Broadening the Scope of Epidemiology
  5. Open Forum Infectious Diseases — Pulmonary Infections Associated with Trametes elegans and Peniophora incarnata
  6. Chromoblastomycosis Basics | CDC

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