Efficacy of different optical zone design with different myopia control for corneal refractive therapy (CRT): a one-year prospective cohort study - Report - MDSpire

Efficacy of different optical zone design with different myopia control for corneal refractive therapy (CRT): a one-year prospective cohort study

  • By

  • Wei-Xia Lai

  • Meng-Tong Wang

  • Ren-Xiu Fu

  • Xixi Wu

  • Qiu-Ming Hu

  • Yi-Yue Jia

  • Yu-Yi Zhang

  • Dong-Yong Tang

  • Wei-Min Zhang

  • June 8, 2026

  • 0 min

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Clinical Report: Effectiveness of Various Optical Zone Configurations in Myopia Management

Overview

This study evaluates the effectiveness of different optical zone configurations in corneal refractive therapy (CRT) for myopia management in children. Results indicate that smaller optical zones are associated with superior myopia control, particularly in suppressing axial length elongation.

Background

The rising prevalence of myopia in children poses a significant public health challenge, necessitating effective management strategies. Orthokeratology (OK) lenses have emerged as a popular option for myopia control, allowing for clear vision during the day while potentially slowing myopia progression. Understanding the impact of optical zone design on treatment efficacy is crucial for optimizing patient outcomes.

Data Highlights

{'Low Myopia 6.0': {'Axial Length Change': 'Data needed'}, 'Mod Myopia 6.0': {'Axial Length Change': 'Data needed'}, 'Low Myopia 5.0': {'Axial Length Change': 'Data needed'}, 'Mod Myopia 5.0': {'Axial Length Change': 'Data needed'}}

Key Findings

  • Smaller optical zones (5 mm, 5.5 mm) are more effective in suppressing axial length elongation compared to larger zones.
  • Individualized fitting based on corneal morphology and visual demands enhances myopia control efficacy.
  • Participants adhered to a strict wearing schedule of at least 8 hours per night.
  • Follow-up evaluations included assessments of naked vision, ocular surface health, and corneal reshaping.
  • Comprehensive evaluations are essential for optimizing therapeutic outcomes in myopia management.

Clinical Implications

Clinicians should consider the optical zone size when prescribing OK lenses for myopia management in children. Tailoring lens design to individual patient characteristics can enhance treatment efficacy and improve visual outcomes.

Conclusion

The study underscores the importance of optical zone configuration in CRT for myopia control, highlighting the need for personalized approaches in pediatric patients. Continued research is essential to refine these strategies further.

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- The effect of orthokeratology lens optical zone size on myopia control in adolescents
  2. Contact Lens Spectrum, 2026 -- Optimizing Treatment in Low Myopes
  3. Contact Lens Spectrum, 2022 -- MASTERING MYOPIA
  4. Contact Lens Spectrum, 2023 -- MASTERING MYOPIA
  5. MYOPIA CONSENSUS STATEMENT -2025
  6. Effect of Optical Zone Diameter in Orthokeratology on Myopia Control: A Meta-Analysis and Systematic Review - PubMed
  7. Incidence of microbial keratitis associated with overnight orthokeratology: a multicenter collaborative study - PubMed
  8. MYOPIA CONSENSUS STATEMENT -2025
  9. Effect of Optical Zone Diameter in Orthokeratology on Myopia Control: A Meta-Analysis and Systematic Review - PubMed
  10. Incidence of microbial keratitis associated with overnight orthokeratology: a multicenter collaborative study - PubMed

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