Conduction Abnormalities Following Combined Surgical and Transcatheter Approaches for Severe Aortic Stenosis and Coronary Artery Disease - Report - MDSpire

Conduction Abnormalities Following Combined Surgical and Transcatheter Approaches for Severe Aortic Stenosis and Coronary Artery Disease

  • By

  • Zulfugar T. Taghiyev

  • Emrah C. Karabacak

  • Martin V. Fuchs

  • Katharina E. Jaeger

  • Balli Chapugi

  • Oliver Dörr

  • Peter Roth

  • Andreas Böning

  • February 13, 2026

  • 0 min

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Clinical Report: Conduction Abnormalities Following Combined Surgical and Transcatheter Approaches

Overview

This study evaluates conduction abnormalities and the need for permanent pacemaker implantation (PPI) in patients with severe aortic stenosis and concomitant coronary artery disease undergoing either TAVR + PCI or SAVR + CABG. The findings highlight significant differences in the incidence of conduction disturbances between the two approaches.

Background

Conduction abnormalities are a common complication following aortic valve interventions, particularly in patients with severe aortic stenosis and coronary artery disease. With the increasing use of TAVR as a treatment option, understanding the implications of these complications is crucial for optimizing patient outcomes. The study addresses the clinical significance of PPI in this patient population and compares the outcomes of different therapeutic strategies.

Data Highlights

{'SAVR + CABG': {'PPI Rate': 'Specify actual data'}, 'TAVR + PCI': {'PPI Rate': 'Specify actual data'}}

Key Findings

  • Conduction disturbances are prevalent in both SAVR + CABG and TAVR + PCI procedures.
  • PPI is often required due to high-grade atrioventricular block following valve interventions.
  • The incidence of conduction abnormalities varies significantly between TAVR and SAVR approaches.
  • Self-expanding TAVR prostheses are associated with increased risk of conduction disturbances.
  • Long-term outcomes related to PPI following these interventions remain poorly understood.

Clinical Implications

Clinicians should be aware of the heightened risk of conduction abnormalities and the potential need for PPI in patients undergoing TAVR, especially those with complex CAD. Careful patient selection and procedural planning are essential to mitigate these risks and improve outcomes.

Conclusion

The study underscores the importance of understanding conduction abnormalities in patients with severe aortic stenosis and coronary artery disease, particularly when choosing between TAVR and SAVR. Further research is needed to clarify the long-term implications of PPI in these patients.

References

  1. Elnur Imanov et al., Pediatric Cardiology, 2020 -- Proceedings of the PICS-AICS Virtual Symposium Held from September 10 to 12, 2020
  2. Clinical Research in Cardiology, 2011 -- Utilizing Surface and Intracardiac Electrocardiograms to Differentiate Conduction Abnormalities Following CoreValve Implantation
  3. Clinical Research in Cardiology, 2020 -- Clinical Outcomes in Patients Exhibiting Dual Conduction Pathways in the Atrioventricular Node: Findings from a Multicenter Observational Study
  4. 2025 ESC/EACTS Guidelines for the management of valvular heart disease | European Heart Journal | Oxford Academic
  5. Risk prediction models for permanent pacemaker implantation following transcatheter aortic valve replacement: a systematic review and meta-analysis - PubMed
  6. Pediatric Cardiology — The Role of Routine Coronary CT Angiography in Assessing Patients with Transposition of the Great Arteries Post-Arterial Switch Operation
  7. Minimizing Permanent Pacemaker Implantation After TAVR: Current Strategies, Monitoring Pathways, and Future Directions
  8. 2025 ESC/EACTS Guidelines for the management of valvular heart disease | European Heart Journal | Oxford Academic
  9. Risk prediction models for permanent pacemaker implantation following transcatheter aortic valve replacement: a systematic review and meta-analysis - PubMed

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