In vivo coronary stent evaluation using photon-counting computed tomography: diagnostic performance - Report - MDSpire
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Assessment of Coronary Stents in Vivo Through Photon-Counting Computed Tomography: A Study of Diagnostic Efficacy

  • By

  • Pietro G. Lacaita

  • Valentin Bilgeri

  • Philipp Spitaler

  • Benedikt Kindl

  • Wolfgang Dichtl

  • Ivan Lechner

  • Sebastian Reinstadler

  • Guy Friedrich

  • Gerlig Widmann

  • Gudrun M. Feuchtner

  • September 19, 2026

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Clinical Report: Assessment of Coronary Stents in Vivo Through Photon-Counting CT

Overview

This study evaluates the diagnostic performance of ultrahigh-resolution photon-counting computed tomography (PCCT) for assessing coronary stents, particularly in detecting in-stent restenosis (ISR). It compares PCCT's image quality with that of conventional energy-integrating detector CT (EID-CT) using invasive coronary angiography (ICA) as the reference standard.

Background

Coronary computed tomography angiography (CTA) is recommended as a first-line diagnostic strategy for suspected chronic coronary syndromes. However, conventional EID-CT faces challenges in accurately assessing coronary stents due to artifacts that can lead to overestimation of stenosis severity. There is a need for improved imaging techniques, such as PCCT, which may enhance the evaluation of stented coronary arteries.

Data Highlights

No numerical or trial data provided in the source material.

Key Findings

  • PCCT offers higher spatial resolution and lower electronic noise compared to EID-CT.
  • PCCT improves visualization of coronary in-stent lumina and reduces artifacts from stent struts.
  • Conventional CTA shows diminished accuracy for small-diameter stents (< 3 mm).
  • Current guidelines recommend caution in using CTA for stents < 3 mm in diameter.
  • Evidence on the in vivo performance of PCCT for coronary stent assessment is still limited.

Clinical Implications

Clinicians should consider the advantages of PCCT in patients with stents, especially those with larger diameters.

Conclusion

PCCT represents a new method in the assessment of coronary stents.

Related Resources & Content

  1. European Radiology, 2023 -- Evaluation of Coronary Stent Patency Using Ultra-High-Resolution Photon-Counting Detector CT: A Comparison with Invasive Coronary Angiography
  2. European Radiology, 2024 -- High-Resolution 40 keV Virtual Monoenergetic Imaging via Spectral Photon-Counting CT in Patients at Elevated Risk for Coronary Stenosis
  3. European Radiology, 2023 -- Evaluation of Virtual Monochromatic Imaging for Coronary Artery Assessment Using Spectral Photon-Counting CT Compared to Dual-Layer CT: A Phantom and Initial Human Investigation
  4. European Radiology, 2025 -- Enhancing Diagnostic Accuracy and Image Clarity in Photon-Counting Coronary CT Angiography Through an Innovative Reconstruction Technique
  5. 2024 ESC Guidelines for the management of chronic coronary syndromes | European Heart Journal | Oxford Academic
  6. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines
  7. SCCT 2021 Expert Consensus Document on Coronary Computed Tomographic Angiography: A Report of the Society of Cardiovascular Computed Tomography - PMC
  8. Coronary Stent Imaging with Photon-counting Detector CT | Radiology: Cardiothoracic Imaging
  9. In vivo coronary stent evaluation using photon-counting computed tomography: diagnostic performance | European Radiology | Springer Nature Link
  10. Diagnostic accuracy of photon-counting CT for in-stent restenosis: A preliminary meta-analysis - PubMed
  11. 2024 ESC Guidelines for the management of chronic coronary syndromes | European Heart Journal | Oxford Academic
  12. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines | JACC
  13. SCCT 2021 Expert Consensus Document on Coronary Computed Tomographic Angiography: A Report of the Society of Cardiovascular Computed Tomography - PMC
  14. Coronary Stent Imaging with Photon-counting Detector CT | Radiology: Cardiothoracic Imaging
  15. In vivo coronary stent evaluation using photon-counting computed tomography: diagnostic performance | European Radiology | Springer Nature Link
  16. Diagnostic accuracy of photon-counting CT for in-stent restenosis: A preliminary meta-analysis - PubMed

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