Mirror therapy combined with defecation motor imagery and repetitive transcranial magnetic stimulation improves post-stroke constipation: a retrospective study with EEG biomarker analysis - Report - MDSpire

Mirror therapy combined with defecation motor imagery and repetitive transcranial magnetic stimulation improves post-stroke constipation: a retrospective study with EEG biomarker analysis

  • By

  • Jiansong Yu

  • Jingyuan Lin

  • July 10, 2026

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Combination of Mirror Therapy, Defecation Motor Imagery, and rTMS Enhances Bowel Function

Overview

This study evaluates the effectiveness of a combined intervention of mirror therapy, defecation motor imagery, and repetitive transcranial magnetic stimulation (rTMS) in improving bowel function in post-stroke patients with constipation. Results indicate significant improvements in bowel function metrics.

Background

Post-stroke constipation is a common complication, particularly following frontal lobe infarction. Traditional rehabilitation strategies often overlook bowel dysfunction.

Data Highlights

Outcome MeasureIntervention GroupControl Group
Wexner Constipation ScoreSignificant improvement (P < 0.01)No significant change
Weekly Bowel FrequencySignificant improvement (P < 0.01)No significant change
PAC-QOLSignificant improvement (P < 0.01)No significant change

Key Findings

  • The intervention group showed greater improvement in Wexner Constipation Score compared to controls (P < 0.01).
  • Weekly bowel frequency increased significantly in the intervention group (P < 0.01).
  • PAC-QOL scores improved significantly in the intervention group (P < 0.01).
  • EEG μ/β-band ERD was enhanced in the intervention group.
  • Moderate correlation (r = 0.56) between ERD changes and Wexner score improvement.

Clinical Implications

Clinicians should consider the potential of these interventions for patients with bowel dysfunction following stroke.

Conclusion

The combination of mirror therapy, motor imagery, and rTMS appears to enhance bowel function in post-stroke patients.

Related Resources & Content

  1. Frontiers in Neurology, 2026 -- Transcranial magnetic stimulation combined with functional near-infrared spectroscopy to elucidate the neurophysiological mechanisms of post-stroke hemiplegia: a systematic review
  2. DIGITAL HEALTH, 2026 -- Unilateral and bilateral digital mirror visual feedback with different movement types modulate mu oscillations in individuals with stroke
  3. Frontiers in Neurology, 2026 -- The effect of non-invasive brain stimulation combined with motor imagery on upper limb motor function and activities of daily living in stroke patients: A systematic review and Meta-analysis
  4. Frontiers in Neurology, 2026 -- Differential cortical responses of robot-assisted active and mirror therapy task conditions in stroke patients and healthy controls: a comparative fNIRS study
  5. Prevalence, Trajectory, and Factors Associated With Patient-Reported Nonmotor Outcomes After Stroke: A Systematic Review and Meta-Analysis - PubMed
  6. Evaluation and management of refractory constipation – American Gastroenterological Association
  7. Autonomic dysfunction after stroke: an overview of recent clinical evidence and perspectives on therapeutic management - PubMed
  8. Prevalence, Trajectory, and Factors Associated With Patient-Reported Nonmotor Outcomes After Stroke: A Systematic Review and Meta-Analysis - PubMed
  9. Evaluation and management of refractory constipation – American Gastroenterological Association
  10. Autonomic dysfunction after stroke: an overview of recent clinical evidence and perspectives on therapeutic management - PubMed

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