Hybrid eclipse: a case of isolated renal tuberculosis with an unusual infectious–inflammatory–neoplastic triad - Report - MDSpire

Uncommon Presentation of Isolated Renal Tuberculosis with a Distinct Infectious-Inflammatory-Neoplastic Triad

  • By

  • Sachin Dharwadkar

  • Vijaykumar Ramu

  • Kavitha B. Chittaragi

  • Suchitha Sathish

  • Sudha Kiran Das

  • Sajan Sehgal

  • July 17, 2026

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Clinical Report: Uncommon Presentation of Isolated Renal Tuberculosis

Background

Isolated renal tuberculosis is a rare extrapulmonary manifestation of tuberculosis that can mimic urinary tract infections, leading to delayed diagnosis.

Data Highlights

No numerical or trial data available in the source material.

Key Findings

  • The patient was a 77-year-old diabetic man with a history of renal calculus disease and recurrent urinary tract infections.
  • Diagnostic imaging revealed extensive renal destruction and a hyperenhancing mass suggestive of renal cell carcinoma.
  • Histopathological examination confirmed renal tuberculosis and its associated complications post-nephrectomy.
  • Antitubercular therapy resulted in stable clinical and functional outcomes.

Clinical Implications

Early imaging and histopathological assessment are crucial for the timely diagnosis of isolated renal tuberculosis.

Conclusion

This case highlights the indolent nature of isolated renal tuberculosis.

Related Resources & Content

  1. Infection — Tuberculosis of the Peritoneum, 2025 -- https://link.springer.com/article/10.1007/s15010-025-02677-8
  2. Recommendations from the German S3 Guidelines on Diagnostic and Prognostic Assessment in Renal Cell Tumors, 2022 -- https://link.springer.com/article/10.1007/s00345-022-03972-x
  3. Diagnostic Imaging Techniques for Evaluating Renal Tumors and Assessing Treatment Response, 2018 -- https://link.springer.com/article/10.1007/s00345-018-2342-3
  4. Frontiers in Oncology — Coexistence of rectal adenocarcinoma and rectal and lymph node tuberculosis: a case report with a limited narrative review
  5. EAU Guidelines on Urological Infections 2025
  6. NICE Guidance on Tuberculosis Recommendations
  7. WHO Consolidated Guidelines on Tuberculosis: Module 3 - Diagnosis
  8. WHO consolidated guidelines on tuberculosis: module 4: treatment and care
  9. ATS/CDC/ERS/IDSA Clinical Practice Guideline Update on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis
  10. Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis - PMC

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