Prediction models for mortality in patients with sepsis: a systematic review and meta-analysis - Report - MDSpire

Prediction models for mortality in patients with sepsis: a systematic review and meta-analysis

  • By

  • Siyuan Lei

  • Huanrong Ruan

  • Jun Wang

  • Guixiang Zhao

  • Hulei Zhao

  • Jianping Liu

  • Jiansheng Li

  • June 10, 2026

  • 0 min

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Clinical Report: Systematic Review and Meta-Analysis of Mortality Prediction Models in Sepsis Patients

Overview

{'AUC': '0.794 (95% CI: 0.755–0.834)'}

Background

{'reference': 'Add citation for global incidence and mortality statistics.'}

Data Highlights

{'explanation': 'Include significance of AUC metric.'}

Key Findings

{'clarification': 'Ensure percentages for calibration and decision curve analysis are accurate.'}

Clinical Implications

{'actions': 'Suggest specific actions for clinicians based on predictors.'}

Conclusion

{'emphasis': 'Reiterate importance of addressing biases.'}

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- Prediction models for the occurrence and mortality of sepsis-associated lung injury: a systematic review and meta-analysis
  2. Intensive Care Medicine, 2022 -- Mortality Prediction Models for Patients Undergoing ECMO: A Systematic Review of Their Characteristics and Performance
  3. Critical Care (Springer), 2025 -- Predictive enrichment using biomarkers in studies of critically-ill patients with sepsis: a systematic review
  4. Intensive Care Medicine, 2019 -- Utilizing Machine Learning to Forecast Sepsis: A Comprehensive Review and Meta-Analysis of Diagnostic Accuracy
  5. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 | SCCM
  6. New England Journal of Medicine -- Early, Goal-Directed Therapy for Septic Shock — A Patient-Level Meta-Analysis
  7. Frontiers, 2026 -- Prediction models for mortality in patients with sepsis: A systematic review and meta-analysis
  8. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 | SCCM
  9. Early, Goal-Directed Therapy for Septic Shock — A Patient-Level Meta-Analysis | New England Journal of Medicine
  10. Frontiers | Prediction models for mortality in patients with sepsis: A systematic review and meta-analysis

Original Source(s)

Prediction models for mortality in patients with sepsis: a systematic review and meta-analysis

  • by Siyuan Lei, Huanrong Ruan, Jun Wang, Guixiang Zhao, Hulei Zhao, Jianping Liu, Jiansheng Li

  • June 10, 2026

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