Residual risk of HIV, HBV, and HCV transmission through blood transfusion in Borgou, Benin, 2023–2025 - Report - MDSpire

Residual risk of HIV, HBV, and HCV transmission through blood transfusion in Borgou, Benin, 2023–2025

  • By

  • Kamel-Dine Djaliri

  • Adolphe Adjanohoun

  • Pamphile Aguessy

  • Victorien Dougnon

  • Haziz Sina

  • Lamine Baba-Moussa

  • June 4, 2026

  • 0 min

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Clinical Report: Assessment of Remaining Risks for HIV, HBV, and HCV Transmission

Overview

This study estimates the residual risk of HIV, HBV, and HCV transmission via blood transfusion in Borgou, Benin, revealing significant incidence rates and highlighting the need for improved screening methods. The findings indicate a lower risk compared to other sub-Saharan African regions but still higher than in high-income countries.

Background

Blood transfusion is essential in healthcare, particularly for maternal and pediatric patients, yet it poses risks of transmitting infections such as HIV, HBV, and HCV. Understanding these risks is crucial for enhancing transfusion safety, especially in resource-limited settings where the prevalence of these infections remains high. This study addresses the urgent need for effective donor selection and screening strategies to mitigate these risks.

Data Highlights

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Key Findings

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Clinical Implications

Healthcare providers should be aware of the residual risks associated with blood transfusions in low-resource settings and advocate for enhanced screening methods, including nucleic acid testing. Strengthening donor selection criteria and health education initiatives is essential to further reduce the transmission risks of TTIs.

Conclusion

The study underscores the importance of continuous improvement in blood safety measures in Borgou, Benin, to align with global standards and reduce the risk of transfusion-transmissible infections.

Related Resources & Content

  1. Open Forum Infectious Diseases, 2021 -- Mortality Rates Associated with Chronic Liver Diseases Due to Hepatitis B and C Infections in African Nations: An Analysis from 1990 to 2021 with Future Projections to 2030
  2. Open Forum Infectious Diseases, 2024 -- Prevalence of Chronic Hepatitis B Virus Infection in HIV-Positive Individuals in Yunnan Province, China: A Retrospective Cohort Analysis (2004–2024)
  3. The Journal of Infectious Diseases, 2023 -- Circulating Hepatitis B Virus (HBV) RNA and Conventional Markers in Treatment-Naive Persons With HBV in Senegal
  4. Open Forum Infectious Diseases — Seroconversion Rates of Hepatitis D Virus in Individuals with Chronic Hepatitis B Virus Infection in France and The Gambia (Inci-D Study)
  5. Blood safety and availability
  6. Standards for Blood Banks and Transfusion Services
  7. Position Statement on Estimated Residual Risk
  8. Guide to the preparation, use and quality assurance of blood components - European Directorate for the Quality of Medicines & HealthCare
  9. https://cdn.who.int/media/docs/default-source/biologicals/blood-products/document-migration/resriskgl_who_trs_1004_web_annex_4.pdf?sfvrsn=55dd09d3_3
  10. TRANSFUSION RISK OF HIV, HBV AND HCV IN LOW-AND-MIDDLE-INCOME COUNTRIES
  11. Guidance on implementing patient blood management to improve global blood health status
  12. Seroprevalence of Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) Among Blood Donors in Borgou, Benin in 2023: A Cross-Sectional Study - PMC
  13. Frontiers | Residual risk of HIV, HBV, and HCV transmission through blood transfusion in Borgou, Benin, 2023–2025
  14. Seroprevalence of Transfusion-transmissible Infections Among Blood Donors at the THIES Regional Hospital Blood Bank, Senegal (January–June 2024), International Journal of Immunology, Science Publishing Group
  15. Clinical Testing Guidance for Blood Safety | Blood Safety | CDC

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