Insights into epidemiological and clinical burden of bronchiolitis among hospitalized children: a call for preventive interventions - Report - MDSpire

Insights into epidemiological and clinical burden of bronchiolitis among hospitalized children: a call for preventive interventions

  • By

  • Rahaf Abughosh

  • Fatmah Almesmari

  • Noora Alattar

  • Bilal Mohammad

  • Basheer Tharayil

  • Maimunah Uddin

  • Stefan Weber

  • Sareea AlRemeithi

  • May 28, 2026

  • 0 min

Share

Clinical Report: Understanding the Epidemiological and Clinical Impact of Bronchiolitis

Overview

This study characterizes the clinical epidemiology, seasonal trends, and risk factors for bronchiolitis hospitalization in infants under 2 years at Sheikh Khalifa Medical City. Key findings include a significant association between prolonged length of stay and factors such as hypoxia, hypercapnia, and comorbidities.

Background

Bronchiolitis is a leading cause of hospitalization in infants, particularly during seasonal peaks, which places a significant burden on healthcare systems. The predominant pathogen is respiratory syncytial virus (RSV), and management remains largely supportive due to the lack of effective antiviral therapies.

Data Highlights

MetricValue
Total Patients598
Mean Age (months)7.8 ± 5.5
Male Patients (%)59
RSV Positive Cases (%)47
Median Length of Stay (days)2.7 (IQR 1.5–5)
Median Hospitalization Cost (AED)21,776

Key Findings

  • Bronchiolitis accounted for 10.4% of pediatric admissions at SKMC.
  • Respiratory distress was the primary reason for admission, with 44% presenting with normoxia and 37% with hypoxia.
  • Prolonged length of stay was significantly associated with hypoxia, hypercapnia, comorbidities, shorter symptom duration, and secondary pneumonia.
  • RSV was identified in 47% of cases, influencing the need for intensive care.
  • 14.9% of patients required admission to the pediatric intensive care unit (PICU).

Clinical Implications

Early identification of infants at risk for prolonged hospitalization due to hypoxia, hypercapnia, or comorbidities is essential for effective resource planning. This study highlights the need for targeted preventive strategies during seasonal peaks of bronchiolitis.

Conclusion

The findings emphasize the importance of understanding the clinical and epidemiological features of bronchiolitis to improve patient management and inform healthcare strategies during peak seasons.

Related Resources & Content

  1. Infection, Current Insights on the Treatment and Management of Pediatric Pneumonia: An In-Depth Review
  2. Infection, Clinical burden of acute respiratory infections in children < 5 years in the emergency room: results from the first season (2023/24) of the RISE study
  3. The Journal of Infectious Diseases, Characterizing the Genetics of Bronchiolitis by Viral Etiology: Is There a Shared Role in Asthma Development?
  4. Infection, Changes in Respiratory Syncytial Virus Seasonality During the COVID-19 Pandemic
  5. High‐Flow Oxygen Therapy vs. Continuous Positive Airway Pressure in Hospitalised Bronchiolitis: A Meta‐Analysis - PMC
  6. Clinical Guidance for RSV Immunizations and Vaccines | RSV | CDC
  7. Comparison of the sensitivity and specificity of bronchiolitis severity scores in infants: a systematic review and meta-analysis
  8. High‐Flow Oxygen Therapy vs. Continuous Positive Airway Pressure in Hospitalised Bronchiolitis: A Meta‐Analysis - PMC
  9. Clinical Guidance for RSV Immunizations and Vaccines | RSV | CDC
  10. Comparison of the sensitivity and specificity of bronchiolitis severity scores in infants: a systematic review and meta-analysis - ScienceDirect

Original Source(s)

Related Content