Application of predicting risk of cardiovascular disease events equations on postoperative major adverse cardiac and cerebral events for patients undergoing thoracic surgery - Report - MDSpire

Application of predicting risk of cardiovascular disease events equations on postoperative major adverse cardiac and cerebral events for patients undergoing thoracic surgery

  • By

  • Wan-Qiu Fan

  • Shuang Wang

  • Er-Yi Zhu

  • Chun-Yu Yu

  • Yi-Kai Liu

  • Hong Li

  • Ke-Xuan Liu

  • Hua-Min Liu

  • July 1, 2026

  • 0 min

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Clinical Report: Utilization of PREVENT Equations for Assessing Cardiovascular Risk

Overview

This study evaluates the association between PREVENT equations and postoperative cardiovascular events in thoracic surgery patients. Findings indicate significant associations in female patients.

Background

Perioperative major adverse cardiac and cerebral events (MACCE) significantly contribute to postoperative mortality and disability, particularly in thoracic surgery. Current risk models often omit critical factors such as blood lipids and kidney function, which are associated with MACCE. The PREVENT equations, developed by the American Heart Association, aim to provide a more comprehensive risk assessment by integrating these factors.

Data Highlights

VariableOdds Ratio (OR)95% Confidence Interval (CI)FDR Corrected P Value
ASCVD Score (Females)1.951.19–3.210.0381
CHD Score (Females, Angina)1.831.14–2.950.0354
CHD Score (Females, AMI)1.461.05–2.030.0386

Key Findings

  • The study included 1,073 patients undergoing thoracic surgery.
  • In females, a 1 SD increase in ASCVD score was linked to higher odds of postoperative angina.
  • CHD score was associated with angina and AMI in female patients.
  • No significant associations were found for males regarding PREVENT risk scores and MACCE.
  • The PREVENT equations showed light to moderate discrimination with AUCs ranging from 0.65 to 0.75 in females.

Clinical Implications

The findings indicate associations between PREVENT equations and cardiovascular risk in female patients undergoing thoracic surgery.

Conclusion

The PREVENT equations demonstrate associations with postoperative MACCE in female thoracic surgery patients.

Related Resources & Content

  1. American Heart Association, 2023 -- PREVENT Equations Frequently Asked Questions
  2. European Journal of Preventive Cardiology, 2023 -- External validation of the 2023 American Heart Association Predicting Risk of cardiovascular disease EVENTs equations
  3. Journal of Medical Internet Research, 2026 -- Multitask Artificial Intelligence–Based Electrocardiogram Tool for Preoperative Cardiac Testing
  4. 2024 AHA/ACC Perioperative CV Management Guideline: Key Points - American College of Cardiology
  5. conexiant — PREVENT Equations Show How Age, Risk Factors Shape CVD Risk
  6. Frontiers in Cardiovascular Medicine — Preoperative cardiovascular evaluation in patients with cancer
  7. PREVENT Equations Show How Age, Risk Factors Shape CVD Risk
  8. 2024 AHA/ACC Perioperative CV Management Guideline: Key Points - American College of Cardiology
  9. American Heart Association PREVENTTM Equations Frequently Asked Questions
  10. Prevalence and trends of perioperative major adverse cardiovascular and cerebrovascular events during cancer surgeries - PMC

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