High-flow nasal oxygen in perioperative and critical care: a bibliometric analysis - Report - MDSpire

High-flow nasal oxygen in perioperative and critical care: a bibliometric analysis

  • By

  • Biao Xi

  • Yuting Zhao

  • Wei Fu

  • Yunzhi Ling

  • Qin Zhuang

  • Di Zhang

  • July 15, 2026

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Clinical Report: Bibliometric Assessment of High-Flow Nasal Oxygen Utilization

Overview

This bibliometric analysis reveals significant growth in high-flow nasal oxygen (HFNO) research, particularly post-2018.

Background

High-flow nasal oxygen (HFNO) is a vital noninvasive respiratory support method in critical care and perioperative settings, improving oxygenation while ensuring patient comfort.

Data Highlights

The analysis included 2,314 unique publications from 2000 to 2025, showing exponential growth in HFNO research.

Key Findings

  • HFNO research has accelerated significantly since 2018, particularly after 2020.
  • The primary contributors to HFNO literature are the United States and China.
  • Major research clusters include acute respiratory failure, perioperative oxygen therapy, and preoxygenation strategies.
  • There is a notable shift in focus from perioperative applications to broader critical care contexts.
  • Current research emphasizes context-specific deployment and monitoring.

Clinical Implications

Understanding the latest trends and evidence in HFNO research can inform clinical decision-making.

Conclusion

HFNO research has transitioned into a diverse field with significant implications for clinical practice.

Related Resources & Content

  1. American Thoracic Society, American Journal of Respiratory and Critical Care Medicine, 2026 -- Noninvasive Respiratory Support for Adult Patients with Acute Respiratory Failure
  2. New England Journal of Medicine, 2026 -- High-Flow or Standard Oxygen in Acute Hypoxemic Respiratory Failure
  3. Frontiers in Medicine — High-Flow Nasal Cannula for Acute Respiratory Failure: A Bibliometric Analysis of Current Trends and Future Directions
  4. Frontiers in Medicine — A comparative study of conventional, High-flow, and jet ventilation via the Wei nasal jet tube for oxygen therapy in patients undergoing bronchoscopic intervention under deep sedation: a randomized controlled trial
  5. Frontiers in Medicine — Respiratory safety and resource utilization in ERCP: a comparative study of high-flow nasal oxygen, conventional mask, and general anesthesia in high-risk populations
  6. Frontiers in Medicine — Summary of the best evidence for adult nasal high-flow oxygen therapy nebulization management
  7. High-Flow Nasal Cannula for Acute Respiratory Failure: A Bibliometric Analysis of Current Trends and Future Directions
  8. A comparative study of conventional, High-flow, and jet ventilation via the Wei nasal jet tube for oxygen therapy in patients undergoing bronchoscopic intervention under deep sedation
  9. Respiratory safety and resource utilization in ERCP: a comparative study of high-flow nasal oxygen, conventional mask, and general anesthesia in high-risk populations
  10. Noninvasive Respiratory Support for Adult Patients with Acute Respiratory Failure. An Official American Thoracic Society Clinical Practice Guideline | American Journal of Respiratory and Critical Care Medicine | Oxford Academic
  11. High-Flow or Standard Oxygen in Acute Hypoxemic Respiratory Failure | New England Journal of Medicine
  12. Non-drug perioperative interventions to reduce postoperative pulmonary complications after abdominal surgery: systematic review and meta-analysis | The BMJ

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