Global Trends and Research Topics in Gastric Bypass Clinical Trials: A Bibliometric Analysis and Latent Dirichlet Allocation (LDA) Study - Report - MDSpire

Global Trends and Research Topics in Gastric Bypass Clinical Trials: A Bibliometric Analysis and Latent Dirichlet Allocation (LDA) Study

  • By

  • Rômulo Ferreira Monteiro

  • Victor Celestino Pires

  • Tiago Rafael Onzi

  • Giovani Firpo Del Duca

  • Jucemar Benedet

  • May 26, 2026

  • 0 min

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Clinical Report: Analysis of Global Patterns in Gastric Bypass Trials

Overview

This report analyzes the global scientific output on gastric bypass (GB) clinical trials from 2001 to 2024, revealing significant increases in both the number of procedures and publications. The findings highlight key research trends and prolific contributors in the field, emphasizing the importance of GB in addressing severe obesity.

Background

Metabolic bariatric surgery (MBS) is a critical intervention for severe obesity, which has become a major public health issue globally. The rising prevalence of obesity necessitates effective treatments, with gastric bypass being one of the most established surgical options. Understanding the research landscape surrounding GB is essential for advancing clinical practices and improving patient outcomes.

Data Highlights

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Key Findings

  • The number of gastric bypass procedures increased from 100,092 in 2014 to 598,736 in 2023.
  • Over 72,000 publications related to gastric bypass were identified in major databases.
  • Gastric bypass is associated with up to a 57% reduction in total body weight five years post-surgery.
  • Bibliometric studies indicate a marked increase in research output since the early 2000s.
  • Gastric bypass remains a key focus in the context of metabolic bariatric surgery despite the rise of sleeve gastrectomy.

Clinical Implications

The findings underscore the importance of gastric bypass as a leading treatment for severe obesity and its associated comorbidities. Clinicians should remain informed about the evolving research landscape to enhance evidence-based practices in bariatric surgery.

Conclusion

This bibliometric analysis provides valuable insights into the global research trends surrounding gastric bypass, highlighting its significance in the management of severe obesity. Continued research and clinical trials are essential for optimizing treatment strategies.

Related Resources & Content

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  7. 8. Obesity and Weight Management for the Prevention and Treatment of Diabetes: Standards of Care in Diabetes-2026 - PubMed
  8. Long-Term Outcomes of Laparoscopic Roux-en-Y Gastric Bypass vs Laparoscopic Sleeve Gastrectomy for Obesity: The SM-BOSS Randomized Clinical Trial | Trials | JAMA Surgery | JAMA Network

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