Exploring the Effects of Frailty and Sarcopenia on Dysphagia in Head and Neck Cancer: A Scoping Review - Report - MDSpire

Investigating the Impact of Frailty and Sarcopenia on Swallowing Difficulties in Patients with Head and Neck Cancer: A Scoping Review

  • By

  • Rishni Perera

  • Elizabeth C. Ward

  • Nicole O'Donnell

  • Paul Yates

  • Rebecca L. Packer

  • July 4, 2026

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Clinical Report: Investigating the Impact of Frailty and Sarcopenia on Swallowing Difficulties in Patients with Head and Neck Cancer

Overview

This scoping review explores the relationship between frailty, sarcopenia, and dysphagia in patients with head and neck cancer (HNC). It highlights the prevalence of these conditions.

Background

Head and neck cancer (HNC) is a significant global health issue, with increasing incidence rates, particularly among older adults. Frailty and sarcopenia are common in this population.

Data Highlights

No numerical data or trial data was provided in the source material.

Key Findings

  • Frailty and sarcopenia are prevalent in patients with head and neck cancer.
  • Dysphagia affects 30% to 60% of patients with HNC.
  • Older age is associated with a higher risk of developing dysphagia in HNC patients.
  • Conditions like frailty and sarcopenia may be associated with dysphagia outcomes following treatment.
  • Sarcopenia is recognized as a contributor to dysphagia.

Clinical Implications

Healthcare providers should consider assessing frailty and sarcopenia in patients with head and neck cancer.

Conclusion

The interplay between frailty, sarcopenia, and dysphagia in head and neck cancer patients is complex.

Related Resources & Content

  1. Perera, H., Head & Neck, 2026 -- Exploring the Effects of Frailty and Sarcopenia on Dysphagia in Head and Neck Cancer: A Scoping Review
  2. ASCO Post, 2019 -- Mitigating Frailty and Sarcopenia to Improve Treatment Outcomes in Lung Cancer
  3. Frontiers in Oncology, 2026 -- Influencing factors of cognitive frailty in older patients with esophageal cancer undergoing chemotherapy: a mixed-methods study
  4. Journal of Medical Internet Research (JMIR) — Effectiveness of Digital Health Interventions in Older Adults With Frailty and Sarcopenia: Systematic Review and Meta‐Analysis of Randomized Controlled Trials
  5. Frontiers in Medicine — Risk prediction models for oral frailty in older adults: a scoping review
  6. NCCN Head and Neck Cancers, Version 1.2026
  7. United Kingdom National Multidisciplinary Guidelines, Sixth edition
  8. ASCO Global Guideline on Geriatric Assessment
  9. Exploring the Effects of Frailty and Sarcopenia on Dysphagia in Head and Neck Cancer: A Scoping Review - Perera - Head & Neck - Wiley Online Library
  10. The use of frailty screening measures for predicting long-term survival outcomes in head and neck cancer: a systematic review - PubMed
  11. Sarcopenia and postoperative morbidity in head & neck cancer: A systematic review and meta-analysis - ScienceDirect
  12. Consensus document on frailty: conceptualization, detection, multidisciplinary management and future roadmap - ScienceDirect
  13. The Effect of Quantitative Goal Exercise Combined with Whole Process Refined Nutrition Management on the Nutritional Status and Quality of Life of Head and Neck Cancer Patients Undergoing Radiotherapy: An Open-Label, Randomized, Controlled Trial - ScienceDirect

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