Case Report: Effective management of acute corneal hydrops with concurrent nystagmus and retinitis pigmentosa: combination of deep lamellar corneal suturing and anterior chamber gas injection - Report - MDSpire

Case Report: Effective management of acute corneal hydrops with concurrent nystagmus and retinitis pigmentosa: combination of deep lamellar corneal suturing and anterior chamber gas injection

  • By

  • Ying Zhou

  • Abudusataer Aishan

  • YanChuan Yang

  • Xia Li

  • May 20, 2026

  • 0 min

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Management of Acute Corneal Hydrops Associated with Nystagmus and Retinitis Pigmentosa

Overview

This case series examines the effective management of acute corneal hydrops in patients with concurrent nystagmus and retinitis pigmentosa through deep lamellar suturing and anterior chamber gas injection. All patients experienced prompt resolution of corneal edema and significant improvement in symptoms post-surgery.

Background

Acute corneal hydrops is a serious complication of keratoconus that can lead to significant visual impairment if not managed properly. The presence of coexisting conditions such as retinitis pigmentosa and nystagmus complicates the clinical picture, making timely and effective treatment essential. Understanding the management strategies for these complex cases can improve patient outcomes and quality of life.

Data Highlights

PatientPreoperative SymptomsPostoperative Outcomes
Patient 1Photophobia, eye painResolved edema, minimal opacities
Patient 2Photophobia, tearingSignificant symptom improvement
Patient 3Eye pain, tearingSuccessful healing, no complications

Key Findings

  • All three patients had acute corneal edema due to rapid keratoconus progression.
  • Deep lamellar corneal suturing combined with anterior chamber gas injection was performed successfully.
  • Postoperative resolution of corneal edema occurred promptly in all cases.
  • No complications such as corneal perforation or neovascularization were observed.
  • Follow-up revealed significant improvement in symptoms and quality of life.

Clinical Implications

The findings suggest that deep lamellar suturing with gas injection is a safe and effective treatment for acute corneal hydrops in patients with keratoconus and associated ocular conditions. Clinicians should consider this approach to prevent severe complications and enhance patient outcomes.

Conclusion

This case series highlights the successful management of acute corneal hydrops in patients with complex ocular conditions, reinforcing the importance of tailored surgical interventions to improve visual prognosis.

Related Resources & Content

  1. Ophthalmology Management, 2012 -- Neurotrophic Keratopathy: New Treatment Strategies
  2. Corneal Physician, 2024 -- MY CORNEAL SAVE: How I Managed a Rare Post-LASIK Occurence
  3. Retinal Physician, 2007 -- Complications of Vitreoretinal Surgery
  4. College of Optometrists, 2025 -- Corneal hydrops
  5. Glaucoma Physician — Postoperative Management of MIGS
  6. Air-Assisted Dome Drainage in Acute Corneal Hydrops: A 3D-OCT-Guided Approach
  7. Essentials of Ocular Anaesthesia: Techniques, Indications, and Complications
  8. Corneal hydrops - College of Optometrists

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