Health Status Changes and Long-Term Clinical Outcomes in Patients With Atrial Fibrillation - Report - MDSpire

Health Status Changes and Long-Term Clinical Outcomes in Patients With Atrial Fibrillation

  • By

  • Takanori Ohata

  • Nobuhiro Ikemura

  • Shun Kohsaka

  • Paul S. Chan

  • Ryo Nakamaru

  • Yasuyuki Shiraishi

  • Ikuko Ueda

  • Takehiro Kimura

  • Yoshinori Katsumata

  • Takahiko Nishiyama

  • Iwao Nakamura

  • Tomohiko Ono

  • Seiji Takatsuki

  • John A. Spertus

  • Masaki Ieda

  • June 15, 2026

  • 0 min

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Changes in Health Status and Long-Term Outcomes in Individuals with Atrial Fibrillation

Overview

This study evaluates the association between changes in Atrial Fibrillation Patient-Reported Outcome Measures (PROMs) and clinical outcomes over one year in patients with atrial fibrillation. Findings suggest that serial improvements in PROM scores may correlate with better long-term clinical outcomes.

Background

Atrial fibrillation (AF) is a leading arrhythmia that significantly impacts mortality and morbidity, necessitating effective management strategies. Optimizing health status through patient-reported outcomes is increasingly recognized as a therapeutic target in AF care. Understanding the relationship between health status changes and clinical outcomes can enhance patient management and risk stratification.

Data Highlights

No numerical data available in the source material.

Key Findings

  • Atrial fibrillation is associated with decreased health status and quality of life.
  • Patient-reported outcome measures (PROMs) can provide insights into the patient experience and support shared decision-making.
  • Lower AF PROM scores at a single time point are linked to adverse clinical outcomes, including heart failure hospitalization.
  • The study utilized data from the KiCS-AF registry, which included over 3000 patients with AF.
  • Changes in AF PROM scores may have prognostic value for clinical outcomes.

Clinical Implications

The findings highlight the importance of monitoring patient-reported outcomes in AF management. Clinicians may consider integrating PROM assessments into routine care to better understand patient health status and inform treatment decisions.

Conclusion

This study underscores the potential prognostic significance of serial AF PROM scores in predicting long-term clinical outcomes in patients with atrial fibrillation.

Related Resources & Content

  1. The ASCO Post, 2021 -- Risk of Atrial Fibrillation and Associated Outcomes After Allogeneic Hematopoietic Stem Cell Transplantation
  2. European Journal of Preventive Cardiology -- Real-world insights for care and outcomes in patients with atrial fibrillation and heart failure
  3. European Journal of Preventive Cardiology -- Heart failure in patients with recently diagnosed atrial fibrillation: findings from the GLORIA-AF Registry Phase III
  4. Clinical Research in Cardiology -- Patients Experiencing Postoperative Atrial Fibrillation After CABG Show Higher Long-Term Atrial Fibrillation Rates and Increased Risks of Ischemic Stroke, Heart Failure, and Mortality Compared to Matched Controls, Even After Adjusting for Atrial Fibrillation Status
  5. Atrial fibrillation - ScienceDirect
  6. CAPLA: Long-Term QOL Improvement With CA For Persistent AFib - American College of Cardiology
  7. Atrial Arrhythmia Burden (SMURDEN) After Ablation of AF Is Associated With Improvement in Quality of Life | JACC: Clinical Electrophysiology
  8. Atrial fibrillation - ScienceDirect
  9. CAPLA: Long-Term QOL Improvement With CA For Persistent AFib - American College of Cardiology
  10. Atrial Arrhythmia Burden (SMURDEN) After Ablation of AF Is Associated With Improvement in Quality of Life | JACC: Clinical Electrophysiology

Original Source(s)

Health Status Changes and Long-Term Clinical Outcomes in Patients With Atrial Fibrillation

  • by Takanori Ohata, Nobuhiro Ikemura, Shun Kohsaka, Paul S. Chan, Ryo Nakamaru, Yasuyuki Shiraishi, Ikuko Ueda, Takehiro Kimura, Yoshinori Katsumata, Takahiko Nishiyama, Iwao Nakamura, Tomohiko Ono, Seiji Takatsuki, John A. Spertus, Masaki Ieda

  • June 15, 2026

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