Patient- and Caregiver-Informed Considerations for the Design and Implementation of Generative AI–Supported Patient-Centered Clinical Decision Support: Qualitative Study - Report - MDSpire

Patient- and Caregiver-Informed Considerations for the Design and Implementation of Generative AI–Supported Patient-Centered Clinical Decision Support: Qualitative Study

  • By

  • Priyanka J Desai

  • Angela Dobes

  • Avantika S Shah

  • Jessica S Ancker

  • Lindsay Abdulhay

  • Sagarika Das

  • Caroline Peterson

  • CDSiC Trust and Patient-Centeredness Workgroup

  • Prashila Dullabh

  • July 14, 2026

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Clinical Report: Incorporating Insights from Patients and Caregivers in PC CDS

Background

The rapid evolution of artificial intelligence (AI) in health care presents opportunities to improve patient outcomes and clinician workflows. Patient-centered clinical decision support (PC CDS) aims to empower patients and caregivers by integrating their preferences and values into health care decision-making. Understanding patient and caregiver perspectives is crucial for the successful implementation of generative AI in these tools.

Data Highlights

No numerical data was provided in the source material.

Key Findings

  • Generative AI can enhance clinical decision-making by streamlining processes and improving outcomes.
  • Patient-centered considerations in CDS include knowledge, data, delivery, and use of patient-specific information.
  • There is a gap in the literature regarding patient perspectives on AI-supported tools for health care decision-making.
  • Previous studies have inadequately incorporated patient insights into AI design and deployment guidance.
  • Qualitative research is needed to gather patient and caregiver perspectives on generative AI in PC CDS.

Clinical Implications

Incorporating patient and caregiver insights into the design and implementation of generative AI tools can enhance trust and usability. This approach may lead to more effective patient-centered care and improved health outcomes.

Conclusion

Addressing the gaps in understanding patient and caregiver perspectives is essential for the effective integration of generative AI in clinical decision support systems.

Related Resources & Content

  1. FDA, Clinical Decision Support Software, 2026 -- Clinical Decision Support Software
  2. Nature Medicine, 2026 -- Generative AI-enabled clinical decision support system in primary care: a pragmatic, cluster-randomized trial
  3. Journal of Medical Internet Research (JMIR), 2026 -- Enhancing Physician Resilience to Generative AI
  4. npj Digital Medicine, 2025 -- Utilization of Generative AI-drafted Responses for Managing Patient-Provider Communication
  5. Journal of Medical Internet Research (JMIR), 2026 -- Artificial Intelligence in Patient-Centered Care
  6. npj Digital Medicine — A qualitative interview study investigating patient, health professional, and developer perspectives on real-world implementation of patient-centered AI systems
  7. Clinical Decision Support Software | FDA
  8. Generative AI-enabled clinical decision support system in primary care: a pragmatic, cluster-randomized trial | Nature Medicine
  9. A Randomized-Clinical Trial of Two Ambient Artificial Intelligence Scribes: Measuring Documentation Efficiency and Physician Burnout - PMC
  10. Performance of predictive AI-based clinical decision support systems across clinical domains: A systematic review and meta-analysis | PLOS Digital Health
  11. Clinical Decision Support (CDS) | Digital Healthcare Research

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