Effectiveness of manual therapy targeting hamstring tightness in knee osteoarthritis: a systematic review of rehabilitation outcomes - Report - MDSpire

Effectiveness of manual therapy targeting hamstring tightness in knee osteoarthritis: a systematic review of rehabilitation outcomes

  • By

  • Saeid Yahia Al Matif

  • Hussain Al Dera

  • Thamer Al Shammary

  • Ahmed Al Mansour

  • Amirah Alotaibi

  • Mona Idris

  • July 2, 2026

  • 0 min

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Clinical Report: Efficacy of Manual Therapy on Hamstring Tightness in KOA

Overview

This systematic review evaluates the effectiveness of manual therapy interventions on hamstring tightness in patients with knee osteoarthritis (KOA).

Background

Knee osteoarthritis (KOA) is a prevalent cause of pain and disability, affecting millions globally. Hamstring tightness can exacerbate symptoms by altering biomechanics and increasing joint loading. Understanding the role of manual therapy in managing hamstring tightness in KOA is crucial for developing effective treatment strategies.

Data Highlights

OutcomeImprovement
Pain (VAS/NPRS)1.5 to 3.2 points
Hamstring Flexibility8 to 18
PEDro Scores3 to 7 (moderate quality)

Key Findings

  • Twelve RCTs with 652 participants were included in the review.
  • Nine studies reported significant within-group improvements in pain and function.
  • Six studies demonstrated significant between-group differences favoring manual therapy.
  • Common biases in studies included lack of therapist blinding and inadequate allocation concealment.
  • Manual therapy techniques such as post-isometric relaxation and soft-tissue mobilization showed consistent short-term benefits.

Clinical Implications

The evidence regarding manual therapy for patients with KOA experiencing hamstring tightness is of moderate quality.

Conclusion

Manual therapy targeting hamstring tightness shows potential for short-term pain relief and functional improvement in KOA.

Related Resources & Content

  1. Clinical Rheumatology, 2018 -- Effectiveness of Home-Based Exercise Therapy on Muscle Strength and Joint Flexibility in Managing Pre-Radiographic Knee Osteoarthritis Among Elderly Individuals: Results from a Randomized Controlled Trial
  2. Clinical Rheumatology, 2021 -- Effectiveness and Economic Impact of Physiotherapy After Total Knee Arthroplasty: A Comprehensive Review and Meta-Analysis
  3. Knee Surgery, Sports Traumatology, Arthroscopy, 2024 -- Outcomes of Proximal Hamstring Tendon Repair: Clinical and MRI Findings at an Average of Three Years Post-Procedure
  4. Knee Surgery, Sports Traumatology, Arthroscopy, 2012 -- Assessment and Outlook of Acute Hamstring Injuries in Athletes
  5. AAOS Clinical Practice Guideline, 2021 -- Osteoarthritis of the Knee
  6. Effectiveness of manual physical therapy and exercise in osteoarthritis of the knee. A randomized, controlled trial
  7. Dynamic soft tissue mobilization versus proprioceptive neuromuscular facilitation in reducing hamstring muscle tightness in patients with knee osteoarthritis: a randomized control trial
  8. https://new.aaos.org/globalassets/quality-and-practice-resources/osteoarthritis-of-the-knee/oak3cpg.pdf

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