Emergency nursing care of a patient with acute appendicitis complicated by esomeprazole-induced anaphylactic shock: a case report - Report - MDSpire
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Management of a Patient with Acute Appendicitis and Anaphylactic Shock Triggered by Esomeprazole: A Case Study

  • By

  • Jiangfeng Pu

  • Li Xin

  • Yikuan Chen

  • Xuemei Jiang

  • September 8, 2026

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Management of a Patient with Acute Appendicitis and Anaphylactic Shock Triggered by Esomeprazole

Overview

This case report details a rare instance of anaphylactic shock induced by esomeprazole in a patient with acute appendicitis, leading to cardiac arrest. The patient received extensive nursing care and advanced interventions.

Background

Acute appendicitis is a common surgical emergency that can lead to severe complications if not treated promptly. Anaphylactic shock, a severe allergic reaction, can occur rapidly and may complicate the management of such patients.

Data Highlights

No numerical data or trial data presented in the article.

Key Findings

  • Anaphylactic shock can occur rapidly after esomeprazole infusion, leading to severe complications such as cardiac arrest.
  • Prompt recognition of allergic reactions and immediate activation of a rapid response team are crucial in managing anaphylactic shock.
  • Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can be an effective intervention in cases of cardiac arrest due to anaphylaxis.
  • Comprehensive nursing care, including monitoring inflammatory markers, is essential for recovery.
  • Multidisciplinary collaboration is vital for improving patient outcomes in critical care settings.

Clinical Implications

Healthcare providers should recognize signs of anaphylaxis in patients receiving medications like esomeprazole, especially in surgical contexts.

Conclusion

This case highlights the need for rapid intervention in managing anaphylactic shock due to drug allergies in surgical patients.

Related Resources & Content

  1. BJS (British Journal of Surgery), 2023 -- Perioperative Drug Allergies and the Risk of Anaphylaxis
  2. Frontiers in Endocrinology, 2026 -- Acute Pheochromocytoma Crisis Induced by Glucocorticoids: Immediate Adrenalectomy with ECMELLA Support
  3. Frontiers in Surgery, 2026 -- Case Report: ERAT-Based Management of Appendiceal Abscess in Early Pregnancy
  4. Part 10: Adult and Pediatric Special Circumstances of Resuscitation | American Heart Association CPR & First Aid, 2025
  5. Diagnosis and Treatment of Acute Appendicitis: 2025 Edition of the World Society of Emergency Surgery Jerusalem Guidelines | Emergency Medicine | JAMA Surgery, 2025
  6. Frontiers in Immunology — From anaphylaxis to eosinophilic esophagitis during omalizumab treatment in a boy with severe asthma and food allergy: a case report
  7. Part 10: Adult and Pediatric Special Circumstances of Resuscitation | American Heart Association CPR & First Aid
  8. Diagnosis and Treatment of Acute Appendicitis: 2025 Edition of the World Society of Emergency Surgery Jerusalem Guidelines | Emergency Medicine | JAMA Surgery | JAMA Network
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